Document Detail

Genomic evolution in domestic cattle: Ancestral haplotypes and healthy beef.
MedLine Citation:
PMID:  21338665     Owner:  NLM     Status:  Publisher    
We have identified numerous Ancestral Haplotypes encoding a 14 Mb region of Bota C!9. Three are frequent in Simmental, Angus and Wagyu and have been conserved since common progenitor populations. Others are more relevant to the differences between these 3 breeds including fat content and distribution in muscle. SREBF1 and Growth Hormone, which have been implicated in the production of healthy beef, are included within these haplotypes. However, we conclude that alleles at these 2 loci are less important than other sequences within the haplotypes. Identification of breeds and hybrids is improved by using haplotypes rather than individual alleles.
Joseph F Williamson; Edward J Steele; Susan Lester; Oscar Kalai; John A Millman; Lindsay Wolrige; Dominic Bayard; Roger L Dawkins
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Publication Detail:
Type:  JOURNAL ARTICLE     Date:  2011-2-18
Journal Detail:
Title:  Genomics     Volume:  -     ISSN:  1089-8646     ISO Abbreviation:  -     Publication Date:  2011 Feb 
Date Detail:
Created Date:  2011-2-22     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  8800135     Medline TA:  Genomics     Country:  -    
Other Details:
Languages:  ENG     Pagination:  -     Citation Subset:  -    
Copyright Information:
Copyright © 2011. Published by Elsevier Inc.
C.Y. O'Connor ERADE Village Foundation, Canning Vale, Western Australia; Division of Health Sciences, Murdoch University, Murdoch, Western Australia.
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