| Genomes, transcriptomes, and proteomes: molecular medicine and its impact on medical practice. | |
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MedLine Citation:
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PMID: 12546609 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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The human genome project and the technological breakthroughs it has produced have moved the field of molecular medicine forward with breathtaking speed. This will impact not only the advance of scientific discoveries and the way science is conducted but also the clinical practice of medicine. In this review we explain the basic principles of these new technologies. Their potential use and impact are demonstrated by using diabetes mellitus as an example of a common and serious medical disorder. Finally, several potentially adverse consequences of "excessive" knowledge are discussed. |
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Authors:
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Ivan C Gerling; Solomon S Solomon; Michael Bryer-Ash |
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Publication Detail:
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Type: Journal Article; Research Support, Non-U.S. Gov't; Review |
Journal Detail:
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Title: Archives of internal medicine Volume: 163 ISSN: 0003-9926 ISO Abbreviation: Arch. Intern. Med. Publication Date: 2003 Jan |
Date Detail:
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Created Date: 2003-01-27 Completed Date: 2003-02-14 Revised Date: 2009-11-19 |
Medline Journal Info:
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Nlm Unique ID: 0372440 Medline TA: Arch Intern Med Country: United States |
Other Details:
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Languages: eng Pagination: 190-8 Citation Subset: AIM; E; IM |
Affiliation:
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Division of Endocrinology, University of Tennessee Health Science Center, VAMC Research 151, 1030 Jefferson Ave, Memphis, TN 38104, USA. igerling@utmem.edu |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Diabetes Mellitus
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genetics,
therapy Gene Expression Profiling Genetic Testing Human Genome Project Humans Molecular Biology* / trends Proteome |
| Chemical | |
Reg. No./Substance:
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0/Proteome |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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