Document Detail

Genome and proteome annotation: organization, interpretation and integration.
MedLine Citation:
PMID:  19019817     Owner:  NLM     Status:  MEDLINE    
Recent years have seen a huge increase in the generation of genomic and proteomic data. This has been due to improvements in current biological methodologies, the development of new experimental techniques and the use of computers as support tools. All these raw data are useless if they cannot be properly analysed, annotated, stored and displayed. Consequently, a vast number of resources have been created to present the data to the wider community. Annotation tools and databases provide the means to disseminate these data and to comprehend their biological importance. This review examines the various aspects of annotation: type, methodology and availability. Moreover, it puts a special interest on novel annotation fields, such as that of phenotypes, and highlights the recent efforts focused on the integrating annotations.
Gabrielle A Reeves; David Talavera; Janet M Thornton
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't; Review    
Journal Detail:
Title:  Journal of the Royal Society, Interface / the Royal Society     Volume:  6     ISSN:  1742-5689     ISO Abbreviation:  J R Soc Interface     Publication Date:  2009 Feb 
Date Detail:
Created Date:  2008-12-24     Completed Date:  2009-03-12     Revised Date:  2013-06-04    
Medline Journal Info:
Nlm Unique ID:  101217269     Medline TA:  J R Soc Interface     Country:  England    
Other Details:
Languages:  eng     Pagination:  129-47     Citation Subset:  IM    
EMBL-EBI, Wellcome Trust Genome Campus, Hinxton, Cambridge CB10 1SD, UK.
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MeSH Terms
Databases, Genetic
Databases, Protein
Genomics / methods*
Molecular Sequence Data
Proteomics / methods*
Reg. No./Substance:

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