Document Detail


Genome sequence of the thermophilic strain Bacillus coagulans 2-6, an efficient producer of high-optical-purity L-lactic acid.
MedLine Citation:
PMID:  21705584     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Bacillus coagulans 2-6 is an efficient producer of lactic acid. The genome of B. coagulans 2-6 has the smallest genome among the members of the genus Bacillus known to date. The frameshift mutation at the start of the d-lactate dehydrogenase sequence might be responsible for the production of high-optical-purity l-lactic acid.
Authors:
Fei Su; Bo Yu; Jibin Sun; Hong-Yu Ou; Bo Zhao; Limin Wang; Jiayang Qin; Hongzhi Tang; Fei Tao; Michael Jarek; Maren Scharfe; Cuiqing Ma; Yanhe Ma; Ping Xu
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't     Date:  2011-06-24
Journal Detail:
Title:  Journal of bacteriology     Volume:  193     ISSN:  1098-5530     ISO Abbreviation:  J. Bacteriol.     Publication Date:  2011 Sep 
Date Detail:
Created Date:  2011-08-12     Completed Date:  2011-10-06     Revised Date:  2012-03-01    
Medline Journal Info:
Nlm Unique ID:  2985120R     Medline TA:  J Bacteriol     Country:  United States    
Other Details:
Languages:  eng     Pagination:  4563-4     Citation Subset:  IM    
Affiliation:
State Key Laboratory of Microbial Metabolism and School of Life Sciences and Biotechnology, Shanghai Jiao Tong University, Shanghai, People’s Republic of China.
Data Bank Information
Bank Name/Acc. No.:
GENBANK/CP002472
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MeSH Terms
Descriptor/Qualifier:
Bacillus / genetics*,  metabolism*
Chromosome Mapping
Fermentation
Frameshift Mutation
Genome, Bacterial*
Lactate Dehydrogenases / genetics,  metabolism
Lactic Acid / biosynthesis*
Molecular Sequence Data
Plasmids
Chemical
Reg. No./Substance:
50-21-5/Lactic Acid; EC 1.1.-/Lactate Dehydrogenases; EC 1.1.1.28/D-lactate dehydrogenase

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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