Document Detail


Genital tuberculosis: a leading cause for infertility in women seeking assisted conception in North India.
MedLine Citation:
PMID:  18283475     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
INTRODUCTION: Genital tuberculosis is a major cause of tubal factor infertility in developing countries. Data regarding the current prevalence of tuberculosis in the infertile population are sparse. AIMS: To determine the incidence of tubal factor infertility in an infertile population seeking assisted reproduction and the prevalence of genital tuberculosis in this sub-group of patients and their symptomatology. MATERIALS AND METHODS: A retrospective analysis of case records of infertile patients registered for in-vitro fertilization (IVF) between January 2007 and June 2007. RESULTS: Hundred and forty women with an indication for IVF were analyzed. Of these, 70 patients (50%) had tubal factor infertility. The prevalence of genital tuberculosis in tubal factor infertility was 34 out of 70 (48.5%). 82.8% of patients with tubal factor had history of prior treatment for tuberculosis. Menstrual abnormalities were seen in only 8 patients: hypomenorrhea (7) and secondary amenorrhea (1). A diagnostic hysteroscopy showed that 11 had uterine adhesions (18.9%) and 1 patient had pale endometrium. Twenty patients out of 70 cases (28.5%) showed evidence of extra genital tuberculosis. CONCLUSION: Genital tuberculosis is the major causative factor for severe tubal disease requiring assisted reproduction in developing countries like India.
Authors:
Neeta Singh; Gurunath Sumana; Suneeta Mittal
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Publication Detail:
Type:  Journal Article     Date:  2008-02-19
Journal Detail:
Title:  Archives of gynecology and obstetrics     Volume:  278     ISSN:  0932-0067     ISO Abbreviation:  Arch. Gynecol. Obstet.     Publication Date:  2008 Oct 
Date Detail:
Created Date:  2008-08-20     Completed Date:  2009-01-05     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  8710213     Medline TA:  Arch Gynecol Obstet     Country:  Germany    
Other Details:
Languages:  eng     Pagination:  325-7     Citation Subset:  IM    
Affiliation:
Department of Obstetrics and Gynecology, All India Institute of Medical Sciences, New Delhi, India.
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MeSH Terms
Descriptor/Qualifier:
Fallopian Tube Diseases / epidemiology,  etiology*
Female
Humans
Incidence
India / epidemiology
Infertility, Female / epidemiology,  etiology*
Prevalence
Retrospective Studies
Tuberculosis, Female Genital / complications*,  epidemiology

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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