Document Detail


Genetics of beta2-adrenergic receptors and the cardiopulmonary response to exercise.
MedLine Citation:
PMID:  18362692     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Exercise elicits a number of physiologic responses to increase oxygen delivery to working muscles. The beta2-adrenergic receptors (ADRB2) play a role in the cardiopulmonary response to exercise. This review is focused on how the gene that encodes the ADRB2 influences the cardiopulmonary response to exercise. In addition, we discuss possible interactions between ADRB2 and other genes important in exercise performance.
Authors:
Eric M Snyder; Bruce D Johnson; Michael J Joyner
Publication Detail:
Type:  Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Review    
Journal Detail:
Title:  Exercise and sport sciences reviews     Volume:  36     ISSN:  0091-6331     ISO Abbreviation:  Exerc Sport Sci Rev     Publication Date:  2008 Apr 
Date Detail:
Created Date:  2008-03-25     Completed Date:  2008-06-24     Revised Date:  2014-09-18    
Medline Journal Info:
Nlm Unique ID:  0375434     Medline TA:  Exerc Sport Sci Rev     Country:  United States    
Other Details:
Languages:  eng     Pagination:  98-105     Citation Subset:  IM    
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MeSH Terms
Descriptor/Qualifier:
Animals
Cardiac Output / physiology
Exercise / physiology*
Genetic Variation
Heart / physiology*
Humans
Lung / physiology*
Polymorphism, Single Nucleotide
Receptors, Adrenergic, beta-1 / genetics
Receptors, Adrenergic, beta-2 / genetics*
Stroke Volume / physiology
Grant Support
ID/Acronym/Agency:
HL54464/HL/NHLBI NIH HHS; HL71478/HL/NHLBI NIH HHS; R01 HL071478/HL/NHLBI NIH HHS; R01 HL071478-05/HL/NHLBI NIH HHS
Chemical
Reg. No./Substance:
0/Receptors, Adrenergic, beta-1; 0/Receptors, Adrenergic, beta-2
Comments/Corrections
Comment In:
Exerc Sport Sci Rev. 2008 Apr;36(2):49-50   [PMID:  18362684 ]

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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