Document Detail


Genetics of Heart Failure in Congenital Heart Disease.
MedLine Citation:
PMID:  23706783     Owner:  NLM     Status:  Publisher    
Abstract/OtherAbstract:
Heart failure is a major problem in the patient with congenital heart disease. Normally interpreted as a sequela of surgical interventions or abnormal preoperative loading conditions, there is increasing evidence that congenital heart malformations and abnormal ventricular function can have the same underlying genetic cause. With the changing demographic characteristics and increasing complexity of care for patients with congenital heart disease, it can be anticipated that heart failure will be a rapidly growing concern in our field. In this article, we aim to give an overview of recent findings from mouse and human models that highlight shared pathways for the regulation of cardiac development and contractility, and their importance for medical care in the near future.
Authors:
Christoph Preuss; Gregor Andelfinger
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Publication Detail:
Type:  JOURNAL ARTICLE     Date:  2013-5-22
Journal Detail:
Title:  The Canadian journal of cardiology     Volume:  -     ISSN:  1916-7075     ISO Abbreviation:  Can J Cardiol     Publication Date:  2013 May 
Date Detail:
Created Date:  2013-5-27     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  8510280     Medline TA:  Can J Cardiol     Country:  -    
Other Details:
Languages:  ENG     Pagination:  -     Citation Subset:  -    
Copyright Information:
Copyright © 2013 Canadian Cardiovascular Society. Published by Elsevier Inc. All rights reserved.
Affiliation:
Service of Cardiology, Centre de Recherche CHU Sainte Justine, Université de Montréal, Montréal, Québec, Canada.
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