| Genetic variation in experimental dental caries in four inbred strains of rats. | |
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MedLine Citation:
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PMID: 8033188 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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The relative contribution of the host genetic effect on the susceptibility to dental caries was examined. Four inbred strains of male rats (BN/Sea, F344/Ms, PVG/cSea, and WKA/Sea) were inoculated with Streptococcus mutans and fed a cariogenic diet. The caries scores of the molar teeth were compared among these four strains, and the degree of genetic determination was estimated by analysis of variance. Statistically significant differences in caries scores were found among these strains (F344 > WKA > PVG/c > BN), and a high degree of genetic determination was obtained. |
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Authors:
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T Kanamoto; K Nonaka; M Nakata |
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Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: Caries research Volume: 28 ISSN: 0008-6568 ISO Abbreviation: Caries Res. Publication Date: 1994 |
Date Detail:
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Created Date: 1994-08-16 Completed Date: 1994-08-16 Revised Date: 2008-11-21 |
Medline Journal Info:
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Nlm Unique ID: 0103374 Medline TA: Caries Res Country: SWITZERLAND |
Other Details:
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Languages: eng Pagination: 156-60 Citation Subset: D; IM |
Affiliation:
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Department of Pediatric Dentistry, Kyushu University Faculty of Dentistry, Fukuoka, Japan. |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Analysis of Variance Animals Colony Count, Microbial Dental Caries Susceptibility / genetics* Diet, Cariogenic Genetic Variation* Male Rats Rats, Inbred BN Rats, Inbred F344 Rats, Inbred Strains Specific Pathogen-Free Organisms Streptococcus mutans / pathogenicity |
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