Document Detail

Genetic variability in response to infection: malaria and after.
MedLine Citation:
PMID:  12209359     Owner:  NLM     Status:  MEDLINE    
Recent studies have shown that the relatively short period of exposure of human populations to malaria has left in its wake a wide range of genetic diversity. And there is growing evidence that other infectious agents have, or are, having the same effect. By integrating further studies of human populations with genetic analyses of susceptibility to murine malaria it should now be possible to determine some of the mechanisms involved in the variation of susceptibility to infectious disease, information which may have important practical implications for both the diagnosis and better management of these conditions.
D J Weatherall; J B Clegg
Related Documents :
3865619 - Genetic and population structure of four sardinian villages.
10674079 - Biased distribution of msp1 and msp2 allelic variants in plasmodium falciparum populati...
17159979 - A genome-wide map of diversity in plasmodium falciparum.
20133889 - African great apes are natural hosts of multiple related malaria species, including pla...
11456319 - Sequence diversity and linkage disequilibrium within the merozoite surface protein-1 (m...
18070099 - Antagonistic effects of a mhc class i allele on malaria-infected house sparrows.
15467919 - Haplotype analysis of the matrix metalloproteinase 3 gene and myocardial infarction in ...
19467449 - Sarcomere mutations in cardiogenesis and ventricular noncompaction.
9951689 - Complete sequence of p53 gene in 20 patients with lung cancer: comparison with chemosen...
Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't; Review    
Journal Detail:
Title:  Genes and immunity     Volume:  3     ISSN:  1466-4879     ISO Abbreviation:  Genes Immun.     Publication Date:  2002 Sep 
Date Detail:
Created Date:  2002-09-04     Completed Date:  2003-05-07     Revised Date:  2008-11-21    
Medline Journal Info:
Nlm Unique ID:  100953417     Medline TA:  Genes Immun     Country:  England    
Other Details:
Languages:  eng     Pagination:  331-7     Citation Subset:  IM    
Weatherall Institute of Molecular Medicine, University of Oxford, John Radcliffe Hospital, Oxford, UK.
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Disease Models, Animal
Erythrocytes / physiology*
Genetic Diseases, Inborn*
Genetic Variation
HLA Antigens / genetics
Hemoglobins / genetics*
Infection / genetics
Malaria / genetics*
Reg. No./Substance:
0/HLA Antigens; 0/Hemoglobins

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

Previous Document:  Toxic epidermal necrolysis: differential diagnosis of an epidermolytic dermopathy in a hematopoietic...
Next Document:  Evidence for a locus (IDDM16) in the immunoglobulin heavy chain region on chromosome 14q32.3 produci...