| Genetic therapy of human neoplastic disease. | |
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MedLine Citation:
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PMID: 7921999 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Molecular biology has provided clinical investigators and basic scientists with the tools to identify those changes present within neoplastic hematopoietic and epithelial cells that lead to the evolution of unregulated patterns of cell growth. This information has made possible the development of therapy that involves genetic modification of either the normal hematopoietic cells (for chemoprotection), or the tumor cells themselves to suppress the growth of these cells. This article will summarize the clinical and laboratory data that is evolving in this area. |
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Authors:
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A B Deisseroth; E G Hanania; S Fu; D Claxton; M Andreeff; R Champlin; J Kavanagh; G Hortobagyi; F Holmes; C Reading |
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Publication Detail:
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Type: Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, P.H.S. |
Journal Detail:
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Title: Journal of hematotherapy Volume: 2 ISSN: 1061-6128 ISO Abbreviation: J Hematother Publication Date: 1993 |
Date Detail:
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Created Date: 1994-11-21 Completed Date: 1994-11-21 Revised Date: 2007-11-15 |
Medline Journal Info:
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Nlm Unique ID: 9306048 Medline TA: J Hematother Country: UNITED STATES |
Other Details:
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Languages: eng Pagination: 373-5 Citation Subset: IM |
Affiliation:
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Department of Hematology, University of Texas M.D. Anderson Cancer Center, Houston 77030. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Animals Cell Transplantation DNA Repair Drug Resistance / genetics Epithelial Cells Gene Therapy* / methods Genes, Retinoblastoma Genetic Vectors Hematopoietic Stem Cell Transplantation Humans Neoplasms / therapy* Neoplastic Stem Cells / transplantation Retroviridae / genetics |
| Grant Support | |
ID/Acronym/Agency:
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P01 CA49639/CA/NCI NIH HHS; P01 CA55164/CA/NCI NIH HHS |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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