| Genetic testing: predictive value of genotyping for diagnosis and management of disease. | |
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MedLine Citation:
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PMID: 23199147 Owner: NLM Status: PubMed-not-MEDLINE |
Abstract/OtherAbstract:
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This article describes predictive, preventive value of genetic tests and the implication of the use of testing for personalized treatment. This year marks the 10th anniversity of publishing of the sequence of the human genome. One important area of application of this mega project is a development of genetic tests for mutation detection in single gene disorders that has impact for pediatric age group patients and analyzing susceptibility genes as risk factors in common disorders. Types of genetic tests, new emerging technologies will enable developments of high-throughput approaches by microarrays of great application capacity as described here. As it is usual for all technologies used in health care, bioethical concerns has to be delt with. The ethical, social and governance issues associated with genetic testing are discussed. |
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Authors:
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Meral Ozgüç |
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Publication Detail:
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Type: Journal Article Date: 2011-05-06 |
Journal Detail:
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Title: The EPMA journal Volume: 2 ISSN: 1878-5085 ISO Abbreviation: EPMA J Publication Date: 2011 Jun |
Date Detail:
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Created Date: 2012-12-03 Completed Date: 2012-12-04 Revised Date: 2012-12-11 |
Medline Journal Info:
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Nlm Unique ID: 101517307 Medline TA: EPMA J Country: Netherlands |
Other Details:
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Languages: eng Pagination: 173-9 Citation Subset: - |
Affiliation:
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Department of Medical Biology, Faculty of Medicine, Hacettepe University, Ankara, Turkey. |
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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