Document Detail

Genetic mapping and assignment of a long-range repeat cluster to band D of chromosome 1 in Mus musculus and M. spretus.
MedLine Citation:
PMID:  1611911     Owner:  NLM     Status:  MEDLINE    
A cluster (D1Lub1) of a long-range repeat family was mapped to the proximal part of the Giemsa-negative band D in Chromosome 1 of Mus musculus and M. spretus by in situ hybridization with cloned probes of the long-range repeat family. By making use of restriction fragment length polymorphisms in DNAs from interspecific backcross mice, the cluster could be mapped to a position 5.3 +/- 2.1 cM distal to the Inha locus and the same distance proximal to the Bcl-2 locus. D1Lub1 was inseparable in 114 meiotic events from Acrg, Sag, and Akp-3. Taken together, the data may serve as a reference for coordinating the genetic and cytogenetic maps of Mus Chromosome 1. High-copy-number variants of the cluster, which appear cytogenetically as homogeneously staining regions at the same chromosome location, presumably arose by amplification of the long-range repeat family in situ.
W Traut; M F Seldin; H Winking
Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, P.H.S.    
Journal Detail:
Title:  Cytogenetics and cell genetics     Volume:  60     ISSN:  0301-0171     ISO Abbreviation:  Cytogenet. Cell Genet.     Publication Date:  1992  
Date Detail:
Created Date:  1992-07-29     Completed Date:  1992-07-29     Revised Date:  2007-11-14    
Medline Journal Info:
Nlm Unique ID:  0367735     Medline TA:  Cytogenet Cell Genet     Country:  SWITZERLAND    
Other Details:
Languages:  eng     Pagination:  128-30     Citation Subset:  IM    
Medizinische Universität zu Lübeck, Institut für Biologie, FRG.
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MeSH Terms
Chromosome Mapping*
Crosses, Genetic
Gene Amplification / genetics
Mice / genetics*
Muridae / genetics*
Nucleic Acid Hybridization
Repetitive Sequences, Nucleic Acid / genetics*
Grant Support

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