Document Detail


Genetic influences on the association between personality risk factors and alcohol use and abuse.
MedLine Citation:
PMID:  12784838     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
The authors assessed the association of 2 personality dimensions with use and abuse of alcohol in 1,320 twin pairs concordantly reporting nonabstinence at age 18.5 years. The 2 alcohol outcomes differentially relate to the 2 personality dimensions: Alcohol-related problems correlate more highly with social deviance than with excitement seeking (ES), and alcohol consumption correlates more highly with ES than with social deviance. Biometric models fit to the data identified similar patterns in genetic covariance, although differences were more evident in genetic correlations between social deviance and alcohol outcomes than in those for ES. Results suggest that genetic influences underlie the association of personality with alcohol use and subsequent problems and illustrate the utility of informative twin analyses in exploring links between genes, personality, and behavior disorder.
Authors:
Brian S Mustanski; Richard J Viken; Jaakko Kaprio; Richard J Rose
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Publication Detail:
Type:  Comparative Study; Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.; Research Support, U.S. Gov't, P.H.S.    
Journal Detail:
Title:  Journal of abnormal psychology     Volume:  112     ISSN:  0021-843X     ISO Abbreviation:  J Abnorm Psychol     Publication Date:  2003 May 
Date Detail:
Created Date:  2003-06-04     Completed Date:  2003-07-08     Revised Date:  2009-11-11    
Medline Journal Info:
Nlm Unique ID:  0034461     Medline TA:  J Abnorm Psychol     Country:  United States    
Other Details:
Languages:  eng     Pagination:  282-9     Citation Subset:  IM    
Affiliation:
Department of Psychology, Indiana University, Bloomington 47405, USA.
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MeSH Terms
Descriptor/Qualifier:
Adult
Alcohol Drinking / epidemiology*,  genetics*,  psychology
Alcoholism / epidemiology*,  genetics*,  psychology
Cohort Studies
Female
Follow-Up Studies
Humans
Male
Personality Disorders / epidemiology*,  genetics*
Questionnaires
Risk Factors
Grant Support
ID/Acronym/Agency:
AA 00145/AA/NIAAA NIH HHS; AA 07611/AA/NIAAA NIH HHS; AA 08315/AA/NIAAA NIH HHS

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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