Document Detail

Genetic and environmental influences on growth.
MedLine Citation:
PMID:  8536182     Owner:  NLM     Status:  MEDLINE    
OBJECTIVES: To provide an overview of the factors associated with growth in primary school children in England and Scotland and to provide information about the secular trend of growth in the last 20 years. SETTING: Representative English and Scottish samples and an English inner city sample. METHODS: The study had a mixed longitudinal design from 1972 to 1994. Between 8000 and 10,000 children participated in each survey. Height was measured in at least 95% of the children in most surveys, and 75% to 85% of parents provided information about family background. Main results are based on published information. Multiple regression was used for most of the analyses. RESULTS: Parents' height, child's birth weight, mother's age at child's delivery, ethnic background and, in white children, family size are the only factors markedly associated with height. Variables that have traditionally been used to assess the possible effect of social conditions were generally not associated with height. The height increase was more marked in Scotland than England over the period 1972 to 1990, and the differences in height of children in the two countries is now minimal. CONCLUSIONS: Most factors cannot be neatly classified as purely genetic or environmental, but seem to indicate that genes are relatively more important. Social factors usually assessed in growth studies do not have an important effect on growth. The marked increase of height over time indicates that the environment and social conditions have allowed children to grow taller. Sibship size is the only factor that was shown to be related to the secular trend in growth.
R J Rona; S Chinn
Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Journal of medical screening     Volume:  2     ISSN:  0969-1413     ISO Abbreviation:  J Med Screen     Publication Date:  1995  
Date Detail:
Created Date:  1996-02-02     Completed Date:  1996-02-02     Revised Date:  2010-03-24    
Medline Journal Info:
Nlm Unique ID:  9433359     Medline TA:  J Med Screen     Country:  ENGLAND    
Other Details:
Languages:  eng     Pagination:  133-9     Citation Subset:  IM    
Department of Public Health Medicine, UMDS St Thomas's Campus, London, United Kingdom.
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MeSH Terms
Body Height / genetics*
England / epidemiology
Ethnic Groups
Infant, Newborn
Longitudinal Studies
Models, Theoretical
Regression Analysis
Respiratory Tract Diseases / epidemiology
Scotland / epidemiology
Tobacco Smoke Pollution
Reg. No./Substance:
0/Tobacco Smoke Pollution

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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