Document Detail


Genetic and environmental influences on alcohol metabolism in humans.
MedLine Citation:
PMID:  11198709     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
This manuscript represents the proceedings of a symposium at the 2000 RSA Meeting in Denver, Colorado. The organizer/chair was Ting-Kai Li. The presentations were: (1) Introduction to the Symposium, by Ting-Kai Li; (2) ALDH2 polymorphism and alcohol metabolism, by Shih-Jiun Yin; (3) ALDH2 promoter polymorphism and alcohol metabolism, by David W. Crabb; (4) Use of BrAC clamping to estimate alcohol elimination rates: Application to studies of the influence of genetic and environmental determinants, by Sean O'Connor; and (5) Effect of food and food composition on alcohol elimination rates as determined by clamping, by Vijay A. Ramchandani.
Authors:
T K Li; S J Yin; D W Crabb; S O'Connor; V A Ramchandani
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Publication Detail:
Type:  Congresses; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, P.H.S.    
Journal Detail:
Title:  Alcoholism, clinical and experimental research     Volume:  25     ISSN:  0145-6008     ISO Abbreviation:  Alcohol. Clin. Exp. Res.     Publication Date:  2001 Jan 
Date Detail:
Created Date:  2001-01-24     Completed Date:  2001-03-22     Revised Date:  2007-11-15    
Medline Journal Info:
Nlm Unique ID:  7707242     Medline TA:  Alcohol Clin Exp Res     Country:  United States    
Other Details:
Languages:  eng     Pagination:  136-44     Citation Subset:  IM    
Affiliation:
Department of Medicine, Indiana University School of Medicine, Indianapolis 46202, USA. tkli@iupui.edu
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MeSH Terms
Descriptor/Qualifier:
Alcohol Dehydrogenase / genetics*,  metabolism
Alcohol Drinking / genetics*,  metabolism
Alcoholism / genetics*,  metabolism
Aldehyde Dehydrogenase / genetics*,  metabolism
Central Nervous System Depressants / metabolism*,  pharmacology
Diet
Environment*
Ethanol / metabolism*,  pharmacology
Food
Genotype
Hemodynamics / drug effects,  genetics
Humans
Polymorphism, Genetic
Grant Support
ID/Acronym/Agency:
P50-AA07611/AA/NIAAA NIH HHS; R01-AA06434/AA/NIAAA NIH HHS; R37-AA02342/AA/NIAAA NIH HHS
Chemical
Reg. No./Substance:
0/Central Nervous System Depressants; 64-17-5/Ethanol; EC 1.1.1.1/Alcohol Dehydrogenase; EC 1.2.1.3/ALDH2 protein, human; EC 1.2.1.3/Aldehyde Dehydrogenase

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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