Document Detail


Genetic defects of lysosomal function in animals.
MedLine Citation:
PMID:  2669879     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
In this article we have described studies using animals with genetic lysosomal defects with particular emphasis on mutant disorders that have contributed toward understanding of pathogenesis and/or management of analogous human conditions. The development of newer strategies in the production and use of animal models will greatly expand the contribution of this resource to biology and medicine.
Authors:
S C Patel; P G Pentchev
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Publication Detail:
Type:  Journal Article; Research Support, U.S. Gov't, Non-P.H.S.; Review    
Journal Detail:
Title:  Annual review of nutrition     Volume:  9     ISSN:  0199-9885     ISO Abbreviation:  Annu. Rev. Nutr.     Publication Date:  1989  
Date Detail:
Created Date:  1989-10-12     Completed Date:  1989-10-12     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  8209988     Medline TA:  Annu Rev Nutr     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  395-416     Citation Subset:  IM    
Affiliation:
Neurology Service, Veterans Administration Medical Center, Newington, Connecticut 06111.
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MeSH Terms
Descriptor/Qualifier:
Animals
Disease Models, Animal*
Lysosomes / metabolism*
Metabolism, Inborn Errors / metabolism*

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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