Document Detail

Genetic counseling for teratogen exposure.
MedLine Citation:
PMID:  3703408     Owner:  NLM     Status:  MEDLINE    
A consecutive series of 200 patients referred for genetic counseling after teratogen exposure was evaluated. One hundred four patients (52%) had exposure to more than one potentially teratogenic agent. One-third of the patients had a positive family history for genetic disease and 10% were of advanced maternal age. Genetic counseling was altered for the majority of patients when all risk factors (age, family history, and multiple teratogen exposure) were considered. Failure to evaluate all aspects of potential risk results in incomplete counseling. The majority of patients (97%) elected to continue their pregnancies after complete counseling. Three of five pregnancy terminations resulted from exposure to documented human teratogens. Precise risk assessment for the teratogen-exposed patient requires thorough genetic counseling to maximize successful pregnancy outcome.
C R King
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Obstetrics and gynecology     Volume:  67     ISSN:  0029-7844     ISO Abbreviation:  Obstet Gynecol     Publication Date:  1986 Jun 
Date Detail:
Created Date:  1986-06-23     Completed Date:  1986-06-23     Revised Date:  2009-10-26    
Medline Journal Info:
Nlm Unique ID:  0401101     Medline TA:  Obstet Gynecol     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  843-6     Citation Subset:  AIM; IM    
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MeSH Terms
Abnormalities, Drug-Induced
Abortion, Therapeutic
Congenital Abnormalities
Contraceptives, Oral / adverse effects
Genetic Counseling*
Genetic Diseases, Inborn / genetics
Reg. No./Substance:
0/Contraceptives, Oral; 0/Teratogens

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