Document Detail


Genetic counseling for teratogen exposure.
MedLine Citation:
PMID:  3703408     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
A consecutive series of 200 patients referred for genetic counseling after teratogen exposure was evaluated. One hundred four patients (52%) had exposure to more than one potentially teratogenic agent. One-third of the patients had a positive family history for genetic disease and 10% were of advanced maternal age. Genetic counseling was altered for the majority of patients when all risk factors (age, family history, and multiple teratogen exposure) were considered. Failure to evaluate all aspects of potential risk results in incomplete counseling. The majority of patients (97%) elected to continue their pregnancies after complete counseling. Three of five pregnancy terminations resulted from exposure to documented human teratogens. Precise risk assessment for the teratogen-exposed patient requires thorough genetic counseling to maximize successful pregnancy outcome.
Authors:
C R King
Related Documents :
9281978 - Fetal alcohol syndrome: the nurse practitioner perspective.
7977408 - Pleural plaques, asbestos exposure, and asbestos bodies in bronchoalveolar lavage fluid.
7129648 - Neurotoxicity of petroleum benzine compared with n-hexane.
3567098 - Choice of control population in studies of adverse reproductive effects of occupational...
8457508 - Ophthalmic findings in classical galactosaemia--prospective study.
1748938 - Indomethacin therapy and fetal urine production in twins with polyhydramnios.
Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Obstetrics and gynecology     Volume:  67     ISSN:  0029-7844     ISO Abbreviation:  Obstet Gynecol     Publication Date:  1986 Jun 
Date Detail:
Created Date:  1986-06-23     Completed Date:  1986-06-23     Revised Date:  2009-10-26    
Medline Journal Info:
Nlm Unique ID:  0401101     Medline TA:  Obstet Gynecol     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  843-6     Citation Subset:  AIM; IM    
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Descriptor/Qualifier:
Abnormalities, Drug-Induced
Abortion, Therapeutic
Congenital Abnormalities
Contraceptives, Oral / adverse effects
Female
Genetic Counseling*
Genetic Diseases, Inborn / genetics
Humans
Male
Pregnancy
Risk
Teratogens*
Chemical
Reg. No./Substance:
0/Contraceptives, Oral; 0/Teratogens

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


Previous Document:  Fetal outcome with oligohydramnios in the second trimester.
Next Document:  Obstetric decision-making: responses to patients who request cesarean delivery.