Document Detail


Genetic basis of sudden cardiac death due to emotional trauma in apparently healthy individuals.
MedLine Citation:
PMID:  20034684     Owner:  NLM     Status:  In-Data-Review    
Abstract/OtherAbstract:
Several mechanisms underlying sudden deaths due to emotional trauma have been propounded. Emotional trauma has been known to be associated with hyperactivation of some physiyological systems including sympathetic system that may directly trigger malign arrhythmic events in arrhythmia-prone subjects or lead to some clinically serious conditions including acute coronary syndromes, Tako-tsubo cardiomyopathy (TTC) etc. that may have the potential to trigger sudden cardiac death (SCD). Besides these well known effects, emotional trauma may be associated with SCDs due to some genetically determined arrhythmogenic conditions including ion channelopathies (overt or obscure), particularly in relatively young victims with no apparent etiology of SCD suggesting thorough evaluation and genetic screening of family members of these victims for prevention of SCD.
Authors:
Kenan Yalta; Okan Onur Turgut; Mehmet Birhan Yilmaz; Ahmet Yilmaz; Izzet Tandogan
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Publication Detail:
Type:  Journal Article     Date:  2010-01-19
Journal Detail:
Title:  International journal of cardiology     Volume:  145     ISSN:  1874-1754     ISO Abbreviation:  Int. J. Cardiol.     Publication Date:  2010 Dec 
Date Detail:
Created Date:  2010-12-14     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  8200291     Medline TA:  Int J Cardiol     Country:  Netherlands    
Other Details:
Languages:  eng     Pagination:  518-9     Citation Subset:  IM    
Copyright Information:
Copyright © 2009 Elsevier Ireland Ltd. All rights reserved.
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