| Genetic analysis of Saccharomyces cerevisiae SY 15 relaxed mutant. | |
MedLine Citation:
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PMID: 6387389 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Evidence is presented showing that the relaxed phenotype of the SY15 mutant is determined by one nuclear recessive mutation. The most characteristic patterns of the relaxed phenotype in yeast - rRNA accumulation and rRNA processing in the absence of protein synthesis were found to segregate together in first and second generation crosses. Therefore, the interruption of rRNA processing that occurs after starvation for a required amino acid is a pleiotropic manifestation of the stringent control itself. It is suggested that the locus for the stringent response in Saccharomyces cerevisiae (designated STR) coordinates the synthesis of rRNA on transcriptional and post-transcriptional levels. |
Authors:
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L I Stateva; P V Venkov |
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Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: Molecular & general genetics : MGG Volume: 195 ISSN: 0026-8925 ISO Abbreviation: Mol. Gen. Genet. Publication Date: 1984 |
Date Detail:
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Created Date: 1984-11-26 Completed Date: 1984-11-26 Revised Date: 2000-12-18 |
Medline Journal Info:
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Nlm Unique ID: 0125036 Medline TA: Mol Gen Genet Country: GERMANY, WEST |
Other Details:
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Languages: eng Pagination: 234-7 Citation Subset: IM |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Genes, Fungal* Genes, Recessive* Genotype Mutation* Phenotype RNA, Ribosomal / genetics, isolation & purification Saccharomyces cerevisiae / genetics* Transcription, Genetic |
| Chemical | |
Reg. No./Substance:
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0/RNA, Ribosomal |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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