Document Detail

Generic and illness-specific quality of life in obsessive-compulsive disorder.
MedLine Citation:
PMID:  20529398     Owner:  NLM     Status:  MEDLINE    
BACKGROUND: Obsessive compulsive disorder (OCD) is a chronic and disabling disorder. It profoundly compromises various aspects of patients' everyday life, thus affecting their quality of life (QoL). Using generic instruments, several studies have confirmed severely impaired health-related QoL in patients diagnosed with OCD. However, there has been a dearth of research on illness-specific QoL. AIMS: The present study aimed to further investigate subjective QoL in individuals with OCD with a focus on illness-specific aspects. METHOD: To assess subjective QoL in a broad OCD sample, an internet survey was conducted with 123 participants with obsessive-compulsive symptoms. The survey comprised both a generic (WHOQOL-BREF) and a novel self-developed OCD-specific QoL measure (QoLOC). Psychopathology was determined with diagnostic standard instruments (self-report forms of: Y-BOCS, OCI-R, BDI-SF). RESULTS: Regression analyses confirmed depression as the best predictor for decreased QoL. In addition, participants reported high despair resulting from OCD-related problems that differed across symptom subtypes. An exploratory factor analysis suggested four domains of OCD-specific problems tapped by the QoLOC: (1) depressiveness in association with OCD; (2) constraints in activities due to OCD symptoms or avoidance; (3) problems with partner and/or family due to OCD symptoms or avoidance; (4) self-concept/coping of own illness. CONCLUSIONS: Results produced a comprehensive picture of QoL impairments and their relation to psychopathology in a representative OCD sample. Illness-specific concerns should be further addressed in QoL research in OCD because such problems are not sufficiently mirrored in generic QoL measures.
Marit Hauschildt; Lena Jelinek; Sarah Randjbar; Birgit Hottenrott; Steffen Moritz
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Publication Detail:
Type:  Journal Article     Date:  2010-06-08
Journal Detail:
Title:  Behavioural and cognitive psychotherapy     Volume:  38     ISSN:  1469-1833     ISO Abbreviation:  Behav Cogn Psychother     Publication Date:  2010 Jul 
Date Detail:
Created Date:  2010-06-24     Completed Date:  2010-10-22     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  9418292     Medline TA:  Behav Cogn Psychother     Country:  United States    
Other Details:
Languages:  eng     Pagination:  417-36     Citation Subset:  IM    
University Medical Center Hamburg-Eppendorf, Hamburg, Germany.
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MeSH Terms
Depressive Disorder / diagnosis,  psychology,  therapy
Disability Evaluation
Health Surveys
Middle Aged
Obsessive-Compulsive Disorder / diagnosis,  psychology*,  therapy
Personality Inventory / statistics & numerical data
Quality of Life / psychology*
Young Adult

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