| Generating Radiofrequency Ablation Lesions Using Magnetically Coupled Bipolar Catheters. | |
| | |
MedLine Citation:
|
PMID: 21501177 Owner: NLM Status: Publisher |
Abstract/OtherAbstract:
|
Background: Transmural lesions are difficult to produce in myocardial regions with thick walls, such as the left ventricle (LV), using conventional radiofrequency (RF) ablation catheters. This study was performed to evaluate the efficacy of magnetically coupled bipolar catheters and compare the performance with conventional unipolar and bipolar RF ablation catheters. Methods and Results: Neodymium magnets assembled in ablation catheters were used to facilitate tissue contact in a bipolar RF ablation system. In vitro sheets of porcine skeletal muscle, with 10-mm thickness, were ablated with a 4-mm-tip unipolar RF ablation catheter (UA), a bipolar ablation system (BA) using a pair of 4-mm-tip catheters, and a magnetically coupled bipolar system (MB). The RF generator setting was 50 W and 90°C. RF energy was delivered for 30 or 60 seconds and five lesions were created in each ablation condition. The bottom side of the skeletal-muscle sheet was exposed to saline at 37°C and a flow of 5.6 L/min, mimicking the LV endocardial surface. The top side was exposed to air, mimicking the epicardial surface. In the 60-second ablation cases, the transmuralities were 0%, 0%, and 40% (UA, BA, and MB, respectively). The volumes of the lesions were 61.5 ± 8.5, 224.3 ± 51.8, and 359.3 ± 93.8 mm(3) (UA, BA, and MB, respectively). Conclusions: The magnetically coupled bipolar RF ablation system created transmural lesions more efficiently than the conventional ablation system, primarily due to higher RF current density and stronger tissue contact. This prototype method could be applied to the development of novel ablation devices for thick areas of tissue.(PACE 2011; 1-5). |
| | |
Authors:
|
Choonghee Lee; Eue-Keun Choi; Hyoun-Joong Kong; Young Bin Choy; Hee Chan Kim; Seil Oh |
Related Documents
:
|
2953367 - Magnetic resonance imaging for assessment of treatment effects in mediastinal hodgkin's... 18661437 - Segmentation of dynamic contrast enhanced magnetic resonance imaging data. 18374717 - Gastric schwannomas: radiological features with endoscopic and pathological correlation. 17504337 - Magnetic resonance imaging for preoperative staging of rectal cancer in clinical practi... 3367777 - Postnatal nmr changes in guinea pig central nervous system: potential relevance to expe... 9674807 - Assessing information in t2-weighted mri scans from secondary progressive ms patients. |
Publication Detail:
|
Type: JOURNAL ARTICLE Date: 2011-4-18 |
Journal Detail:
|
Title: Pacing and clinical electrophysiology : PACE Volume: - ISSN: 1540-8159 ISO Abbreviation: - Publication Date: 2011 Apr |
Date Detail:
|
Created Date: 2011-4-19 Completed Date: - Revised Date: - |
Medline Journal Info:
|
Nlm Unique ID: 7803944 Medline TA: Pacing Clin Electrophysiol Country: - |
Other Details:
|
Languages: ENG Pagination: - Citation Subset: - |
Copyright Information:
|
©2011, The Authors. Journal compilation ©2011 Wiley Periodicals, Inc. |
Affiliation:
|
Biomedical Engineering Internal Medicine, Seoul National University College of Medicine, Seoul, Korea. |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
|
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: Patch, prick or intradermal tests to detect delayed hypersensitivity to corticosteroids?
Next Document: Complex Fractionated Atrial Electrogram or Linear Ablation in Patients with Persistent Atrial Fibril...