Document Detail

Generalized eruptive histiocytoma: report of a pediatric case.
MedLine Citation:
PMID:  8478484     Owner:  NLM     Status:  MEDLINE    
A one-year-old boy was seen with brownish, flat papules on his face, neck and upper arms. The lesions were symmetric, discrete, slightly raised, firm to the touch, and asymptomatic papular eruptions. Histological and immunohistochemical investigation revealed monomorphous infiltration of S-100 negative, lysozyme negative, and alpha 1-antitrypsin negative, but alpha 1-antichymotrypsin positive and vimentin positive histiocytic cells with small numbers of lymphocytic cells. The histiocytic cells did not show any foamy changes in the cytoplasm. No giant cells were found. The lesions increased in number during the first few years and then spontaneously regressed by the sixth year of age, leaving partial brownish pigmentation.
S Izaki; K Kitamura; E Arai
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Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  The Journal of dermatology     Volume:  20     ISSN:  0385-2407     ISO Abbreviation:  J. Dermatol.     Publication Date:  1993 Feb 
Date Detail:
Created Date:  1993-05-24     Completed Date:  1993-05-24     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  7600545     Medline TA:  J Dermatol     Country:  JAPAN    
Other Details:
Languages:  eng     Pagination:  105-8     Citation Subset:  IM    
Department of Dermatology, Saitama Medical Center, Saitama Medical School, Kawagoe, Japan.
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MeSH Terms
Child, Preschool
Fibroma / pathology*
Follow-Up Studies
Histiocytes / pathology
Skin Neoplasms / pathology*
Vimentin / analysis
alpha 1-Antichymotrypsin / analysis
Reg. No./Substance:
0/Vimentin; 0/alpha 1-Antichymotrypsin

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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