| Generalized Paroxysmal Fast Activity and Tonic Seizures in Older Adults. | |
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MedLine Citation:
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PMID: 21946373 Owner: NLM Status: Publisher |
Abstract/OtherAbstract:
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SUMMARY: Generalized paroxysmal fast activity is an uncommon ictal EEG pattern usually associated with tonic seizures. Patients with generalized paroxysmal fast activity typically have multiple seizure types beginning in childhood and are refractory to antiepileptic drug therapy. We describe 3 hospitalized adult patients (age, older than 55 years) with new-onset tonic movements, noted during an acute illness, associated with generalized paroxysmal fast activity on EEG. These seizures were characterized by subtle stiffening of the arms, trunk, and face for up to 3 seconds. All patients had multiple medical problems and polypharmacy. None had a history of static encephalopathy, other epileptiform abnormalities on EEG, other seizure types, or significant neuroimaging abnormalities. In contrast to previously described reports in children, all three adults responded to antiepileptic drug monotherapy. EEG played a critical role in differentiating tonic seizures from nonepileptic movements in these three cases. |
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Authors:
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Amar B Bhatt; Richard P Brenner; Anne C Van Cott |
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Publication Detail:
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Type: JOURNAL ARTICLE Date: 2011-9-23 |
Journal Detail:
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Title: Journal of clinical neurophysiology : official publication of the American Electroencephalographic Society Volume: - ISSN: 1537-1603 ISO Abbreviation: - Publication Date: 2011 Sep |
Date Detail:
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Created Date: 2011-9-27 Completed Date: - Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 8506708 Medline TA: J Clin Neurophysiol Country: - |
Other Details:
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Languages: ENG Pagination: - Citation Subset: - |
Affiliation:
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*Department of Neurology, University of Pittsburgh Medical Center, Pittsburgh, Pennsylvania †Division of Neurology, Veterans' Affairs Pittsburgh Health Care System, Pittsburgh, Pennsylvania. |
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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