| General versus locoregional anesthesia in carotid surgery: a prospective randomised trial. | |
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MedLine Citation:
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PMID: 17109365 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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BACKGROUND: To evaluate the influence of anesthetic technique on perioperative neurological and cardiopulmonary complication rates in patients undergoing carotid endarterectomy. PATIENTS AND METHODS: 186 patients with symptomatic internal carotid artery (ICA) stenosis > 70% or asymptomatic ICA stenosis > 80% were prospectively randomized for either locoregional (LA) or general anesthesia (GA). RESULTS: Neurological complication rates were similar in both groups (GA 2% vs. LA 2%). Cardiopulmonary complication rates were not significantly different (GA 4% vs LA 1%). There were no stroke-related deaths, but one patient from the GA group died from severe postoperative pneumonia. Thus, a significant difference in combined stroke/cardiopulmonary related death between the two groups (GA 1% vs LA 0%) could not be found. However, perioperative cardiopulmonary monitoring showed that significantly more patients operated under general anesthesia had hypertensive events, with systolic blood pressure values greater than 180 mmHg on postoperative day one. There were no differences in the number of postoperatively hypotensive episodes (systolic blood pressure values < 100 mmHg) between the two groups. CONCLUSIONS: Significant differences in the perioperative neurological and cardiopulmonary complication rates between general and locoregional anesthesia in patients undergoing carotid endarterectomy could not be observed. |
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Authors:
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P M Kasprzak; J Altmeppen; M Angerer; S Mann; J Mackh; I Töpel |
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Publication Detail:
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Type: Comparative Study; Journal Article; Randomized Controlled Trial |
Journal Detail:
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Title: VASA. Zeitschrift für Gefässkrankheiten Volume: 35 ISSN: 0301-1526 ISO Abbreviation: VASA Publication Date: 2006 Nov |
Date Detail:
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Created Date: 2006-11-19 Completed Date: 2007-02-28 Revised Date: 2012-10-19 |
Medline Journal Info:
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Nlm Unique ID: 0317051 Medline TA: Vasa Country: Switzerland |
Other Details:
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Languages: eng Pagination: 232-8 Citation Subset: IM |
Affiliation:
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Department of Surgery/Vascular Surgery, Regensburg University Medical Center, Regensburg, Germany. piotr.kasprzak@klinik.uni-regensburg.de |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Aged Aged, 80 and over Anesthesia, Conduction* Anesthesia, General* Carotid Artery, Internal / surgery Carotid Stenosis / surgery* Endarterectomy, Carotid* Female Humans Hypertension / etiology Ischemic Attack, Transient / etiology Male Middle Aged Neurologic Examination Postoperative Complications / etiology* Prospective Studies Respiratory Insufficiency / etiology Risk Factors Stroke / etiology Tachycardia / etiology |
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