Document Detail

General versus locoregional anesthesia in carotid surgery: a prospective randomised trial.
MedLine Citation:
PMID:  17109365     Owner:  NLM     Status:  MEDLINE    
BACKGROUND: To evaluate the influence of anesthetic technique on perioperative neurological and cardiopulmonary complication rates in patients undergoing carotid endarterectomy.
PATIENTS AND METHODS: 186 patients with symptomatic internal carotid artery (ICA) stenosis > 70% or asymptomatic ICA stenosis > 80% were prospectively randomized for either locoregional (LA) or general anesthesia (GA).
RESULTS: Neurological complication rates were similar in both groups (GA 2% vs. LA 2%). Cardiopulmonary complication rates were not significantly different (GA 4% vs LA 1%). There were no stroke-related deaths, but one patient from the GA group died from severe postoperative pneumonia. Thus, a significant difference in combined stroke/cardiopulmonary related death between the two groups (GA 1% vs LA 0%) could not be found. However, perioperative cardiopulmonary monitoring showed that significantly more patients operated under general anesthesia had hypertensive events, with systolic blood pressure values greater than 180 mmHg on postoperative day one. There were no differences in the number of postoperatively hypotensive episodes (systolic blood pressure values < 100 mmHg) between the two groups.
CONCLUSIONS: Significant differences in the perioperative neurological and cardiopulmonary complication rates between general and locoregional anesthesia in patients undergoing carotid endarterectomy could not be observed.
P M Kasprzak; J Altmeppen; M Angerer; S Mann; J Mackh; I Töpel
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Publication Detail:
Type:  Comparative Study; Journal Article; Randomized Controlled Trial    
Journal Detail:
Title:  VASA. Zeitschrift für Gefässkrankheiten     Volume:  35     ISSN:  0301-1526     ISO Abbreviation:  VASA     Publication Date:  2006 Nov 
Date Detail:
Created Date:  2006-11-19     Completed Date:  2007-02-28     Revised Date:  2012-10-19    
Medline Journal Info:
Nlm Unique ID:  0317051     Medline TA:  Vasa     Country:  Switzerland    
Other Details:
Languages:  eng     Pagination:  232-8     Citation Subset:  IM    
Department of Surgery/Vascular Surgery, Regensburg University Medical Center, Regensburg, Germany.
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MeSH Terms
Aged, 80 and over
Anesthesia, Conduction*
Anesthesia, General*
Carotid Artery, Internal / surgery
Carotid Stenosis / surgery*
Endarterectomy, Carotid*
Hypertension / etiology
Ischemic Attack, Transient / etiology
Middle Aged
Neurologic Examination
Postoperative Complications / etiology*
Prospective Studies
Respiratory Insufficiency / etiology
Risk Factors
Stroke / etiology
Tachycardia / etiology

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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