Document Detail


General paresis with reversible mesial temporal T2-weighted hyperintensity on magnetic resonance image: a case report.
MedLine Citation:
PMID:  16425549     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
We report a patient with general paresis, whose magnetic resonance image (MRI) showed a T2 high-intensity lesion in bilateral mesial temporal regions. Serum rapid plasma reagin test showed reactive at 64 dilutions and serum Treponema pallidum haemagglutination test was 1:20480. Cerebrospinal fluid analysis showed: RBC 111/mm3, WBC 8/mm3, Venereal Disease Research Laboratory reactive at 1 dilution and protein 60 mg/dl. His neuropsychiatric symptoms recovered gradually after penicillin treatment two months later. Repeated MRI revealed resolution of the bilateral mesial temporal lesions. We demonstrated the first Taiwanese patient with general paresis whose clinical improvement was associated with the disappearance of the temporal lobe MRI abnormality. The diagnosis of neurosyphilis must be considered when MRI shows mesial temporal lesions. MRI may be used to predict prognosis in patients with general paresis.
Authors:
Chung-Wen Chen; Ho-Chou Chiang; Po-Lin Chen; Peiyuan F Hsieh; Yi-Chung Lee; Ming-Hong Chang
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Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  Acta neurologica Taiwanica     Volume:  14     ISSN:  1028-768X     ISO Abbreviation:  Acta Neurol Taiwan     Publication Date:  2005 Dec 
Date Detail:
Created Date:  2006-01-23     Completed Date:  2006-02-09     Revised Date:  2008-05-28    
Medline Journal Info:
Nlm Unique ID:  9815355     Medline TA:  Acta Neurol Taiwan     Country:  China (Republic : 1949- )    
Other Details:
Languages:  eng     Pagination:  208-12     Citation Subset:  IM    
Affiliation:
Division of Neurology, Taichung Veterans General Hospital, Taiwan.
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MeSH Terms
Descriptor/Qualifier:
Humans
Magnetic Resonance Imaging*
Male
Middle Aged
Neurosyphilis / drug therapy,  pathology*
Penicillin G / therapeutic use
Temporal Lobe / pathology*
Chemical
Reg. No./Substance:
61-33-6/Penicillin G

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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