Document Detail


General medical and ethical problems of drug treatment in the elderly.
MedLine Citation:
PMID:  8953823     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Drug treatment of the elderly raises important concerns regarding medical and ethical issues. Medical problems may arise from age-related changes in social and economic conditions. Furthermore, there is a complexity of influences on the physical and mental state by polymorbidity and polypharmacy, and by alterations in pharmacokinetics and pharmacodynamics. Ethical problems may arise from a conflict of interests between different parties, e.g., between the patient's goal to get the best available treatment and the physican's goal to improve medical knowledge about a certain drug. A central problem in medical ethics is the conflict between two ethical principles: e.g., the principle of respect for the patient's autonomy and the principle of beneficence. The usual solution to this ethical dilemma is to make use of the concept of competence, but it is debatable whether competence is a binary or graded concept. The model of informed consent is based on the patient's competence. But for the purpose of drug treatment of mentally impaired subjects a proxy consent of a legally authorized representative was claimed.
Authors:
R Wolf
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Thérapie     Volume:  51     ISSN:  0040-5957     ISO Abbreviation:  Therapie     Publication Date:    1996 Jul-Aug
Date Detail:
Created Date:  1997-01-07     Completed Date:  1997-01-07     Revised Date:  2006-10-30    
Medline Journal Info:
Nlm Unique ID:  0420544     Medline TA:  Therapie     Country:  FRANCE    
Other Details:
Languages:  eng     Pagination:  424-8     Citation Subset:  IM    
Affiliation:
Centre of Geriatric Medicine and Gerontology, Albert-Ludwigs-University of Freiburg, Germany.
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MeSH Terms
Descriptor/Qualifier:
Aged
Drug Therapy*
Drug Therapy, Combination
Ethics, Medical
Germany
Humans
Medicine
Morbidity
Pharmacokinetics
Socioeconomic Factors

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