Document Detail

General anaesthesia and the hypereosinophilic syndrome: severe postoperative complications in two patients.
MedLine Citation:
PMID:  1467115     Owner:  NLM     Status:  MEDLINE    
Two patients with markedly increased eosinophil counts developed severe postoperative complications after general anaesthesia. One patient suffered life-threatening Adult Respiratory Distress Syndrome (ARDS), while the other presented with a coagulopathy and less severe respiratory problems. The hypereosinophilic syndrome is described and the possibility of a role of eosinophils in the pathogenesis of tissue injury is discussed. These cases suggest that, in patients with marked eosinophilia requiring general anaesthesia, perioperative steroid cover is advisable. This may reduce or prevent serious lung damage and other complications.
G Samsoon; M E Wood; A B Knight-George; R P Britt
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Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  British journal of anaesthesia     Volume:  69     ISSN:  0007-0912     ISO Abbreviation:  Br J Anaesth     Publication Date:  1992 Dec 
Date Detail:
Created Date:  1993-01-28     Completed Date:  1993-01-28     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  0372541     Medline TA:  Br J Anaesth     Country:  ENGLAND    
Other Details:
Languages:  eng     Pagination:  653-6     Citation Subset:  IM    
Department of Anaesthesia, Hillingdon Hospital, Uxbridge, Middlesex.
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MeSH Terms
Anesthesia, General / adverse effects*
Blood Coagulation Disorders / etiology*
Eosinophilia / complications*
Lung Diseases / etiology
Middle Aged
Postoperative Complications*
Respiratory Distress Syndrome, Adult / etiology*

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