Document Detail


Gene transfer into mammalian embryos.
MedLine Citation:
PMID:  3305555     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Transgenic mice provide a unique system fusing classical genetics with molecular biology. They enable the dissection of molecular mechanisms underlying the control of growth and differentiation, issues we only dreamed of 20 years ago. The transgenic technology can be expected to be applied also in areas like eugenetics of animal production systems as well as genetic farming. The technology does not give an acceptable alternative for the direct treatment of human disease. However it provides unique possibilities to study genetic defects in a genetically well-defined mammalian model system. The years to come will teach us which of these expectations will come true.
Authors:
P Krimpenfort; A Berns
Related Documents :
21396575 - Stat5b deficiency: lessons from stat5b gene mutations.
12640275 - Primary ureteral reflux: emerging insights from molecular and genetic studies.
20862485 - Molecular diagnostics of gliomas: the clinical perspective.
10438665 - Coalescing into the 21st century: an overview and prospects of coalescent theory.
3523795 - A dna polymorphism in the human low-density lipoprotein receptor gene.
24736505 - Variation in arabidopsis flowering time associated with cis-regulatory variation in con...
Publication Detail:
Type:  Journal Article; Review    
Journal Detail:
Title:  Human reproduction (Oxford, England)     Volume:  2     ISSN:  0268-1161     ISO Abbreviation:  Hum. Reprod.     Publication Date:  1987 May 
Date Detail:
Created Date:  1987-10-13     Completed Date:  1987-10-13     Revised Date:  2007-11-15    
Medline Journal Info:
Nlm Unique ID:  8701199     Medline TA:  Hum Reprod     Country:  ENGLAND    
Other Details:
Languages:  eng     Pagination:  333-9     Citation Subset:  IM    
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Descriptor/Qualifier:
Animals
Cell Line
Cloning, Molecular*
DNA / administration & dosage
Embryo, Mammalian*
Embryonic Development
Female
Gene Expression Regulation
Mice / genetics*
Microinjections
Mutation
Pregnancy
Zygote
Chemical
Reg. No./Substance:
9007-49-2/DNA

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


Previous Document:  Human fertilization in vivo, with special reference to progression, storage and release of competent...
Next Document:  Historic trials: Montreal Tramways v. Leveillé (1933) 4 DLR 338.