Document Detail

Gene transfer into mammalian embryos.
MedLine Citation:
PMID:  3305555     Owner:  NLM     Status:  MEDLINE    
Transgenic mice provide a unique system fusing classical genetics with molecular biology. They enable the dissection of molecular mechanisms underlying the control of growth and differentiation, issues we only dreamed of 20 years ago. The transgenic technology can be expected to be applied also in areas like eugenetics of animal production systems as well as genetic farming. The technology does not give an acceptable alternative for the direct treatment of human disease. However it provides unique possibilities to study genetic defects in a genetically well-defined mammalian model system. The years to come will teach us which of these expectations will come true.
P Krimpenfort; A Berns
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Publication Detail:
Type:  Journal Article; Review    
Journal Detail:
Title:  Human reproduction (Oxford, England)     Volume:  2     ISSN:  0268-1161     ISO Abbreviation:  Hum. Reprod.     Publication Date:  1987 May 
Date Detail:
Created Date:  1987-10-13     Completed Date:  1987-10-13     Revised Date:  2007-11-15    
Medline Journal Info:
Nlm Unique ID:  8701199     Medline TA:  Hum Reprod     Country:  ENGLAND    
Other Details:
Languages:  eng     Pagination:  333-9     Citation Subset:  IM    
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MeSH Terms
Cell Line
Cloning, Molecular*
DNA / administration & dosage
Embryo, Mammalian*
Embryonic Development
Gene Expression Regulation
Mice / genetics*
Reg. No./Substance:

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