Document Detail


Gene for lipoamide dehydrogenase maps to human chromosome 7.
MedLine Citation:
PMID:  3399966     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
The gene for lipoamide dehydrogenase (LD) has been assigned to human chromosome 7 based on filter hybridization analysis of genomic DNA from rodent-human somatic cell hybrids using a cDNA probe for human LD. No indication of multiple copies of the gene was found, in accordance with previous evidence that LD in the pyruvate, alpha-ketoglutarate, and branched chain alpha-ketoacid dehydrogenase complexes is genetically as well as biochemically identical.
Authors:
G Otulakowski; B H Robinson; H F Willard
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Somatic cell and molecular genetics     Volume:  14     ISSN:  0740-7750     ISO Abbreviation:  Somat. Cell Mol. Genet.     Publication Date:  1988 Jul 
Date Detail:
Created Date:  1988-08-31     Completed Date:  1988-08-31     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  8403568     Medline TA:  Somat Cell Mol Genet     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  411-4     Citation Subset:  IM    
Affiliation:
Research Institute, Hospital for Sick Children, Toronto, Ontario, Canada.
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MeSH Terms
Descriptor/Qualifier:
Chromosome Mapping
Chromosomes, Human, Pair 7*
Dihydrolipoamide Dehydrogenase / genetics*
Humans
Hybrid Cells
Nucleic Acid Hybridization
Chemical
Reg. No./Substance:
EC 1.8.1.4/Dihydrolipoamide Dehydrogenase

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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