Document Detail


Gene expression in elongating and gastrulating embryos from ruminants.
MedLine Citation:
PMID:  17491159     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
In ruminants, more than 30% of the embryonic losses observed after artificial insemination (AI) have an early origin, coincident with a marked elongation of the trophoblast which occurs before implantation. Several observations provide clear evidence that early elongation of the conceptus relies on cell multiplication, cell growth and cell shape remodeling. Recent results indicating an intense multiplication of a non-fully differentiated trophoblast, which still expresses some epiblast genes, has to be considered at the onset of elongation. It has also been shown in the last two years that general metabolism and protein trafficking are characteristic of the onset of elongation whereas cellular interactions, cell to cell signaling and cell adhesion become predominant at the end of elongation. Accordingly, expression of most of the single genes identified so far increases during elongation and is related to the establishment of embryo-maternal exchanges before implantation. However, not much is known of what controls the induction of the elongation process or the coordinated development of the embryonic and extra-embryonic tissues. This review highlights new information on this developmental phase and summarizes the views on the complex cross-talk among molecules which might govern conceptus development and lead to successful implantation.
Authors:
I Hue; S A Degrelle; E Campion; J P Renard
Related Documents :
1289059 - Commitment along the dorsoventral axis of the sea urchin embryo is altered in response ...
10393819 - Energy metabolism during embryonic development and larval growth of an antarctic sea ur...
18156649 - Diagnostic efficiency, embryonic development and clinical outcome after the biopsy of o...
14653899 - Preimplantation genetic diagnosis as a novel source of embryos for stem cell research.
22662279 - Functional interaction between human papillomavirus type 16 e6 and e7 oncoproteins and ...
7086329 - Cell interactions in the developing somite: in vitro comparisons between amputated (am/...
23451069 - Label-free detection of neuronal differentiation in cell populations using high-through...
18726489 - Expression of recombinant rat neurotrophin-3 in chinese hamster ovary cells.
6776019 - Effect of some benzthiazol derivatives on euglena gracilis.
Publication Detail:
Type:  Journal Article; Review    
Journal Detail:
Title:  Society of Reproduction and Fertility supplement     Volume:  64     ISSN:  1747-3403     ISO Abbreviation:  Soc Reprod Fertil Suppl     Publication Date:  2007  
Date Detail:
Created Date:  2007-05-11     Completed Date:  2007-11-05     Revised Date:  2014-06-13    
Medline Journal Info:
Nlm Unique ID:  101295315     Medline TA:  Soc Reprod Fertil Suppl     Country:  England    
Other Details:
Languages:  eng     Pagination:  365-77     Citation Subset:  IM    
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Descriptor/Qualifier:
Animals
Embryonic Development / genetics*
Female
Gastrula / physiology*
Gene Expression
Gene Expression Profiling
Gene Expression Regulation, Developmental*
Microarray Analysis
Pregnancy
Ruminants / physiology*

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


Previous Document:  Gene expression analysis of single preimplantation bovine embryos and the consequence for developmen...
Next Document:  Fetal-maternal interactions during the establishment of pregnancy in ruminants.