Document Detail


Gene expression in the deep biosphere.
MedLine Citation:
PMID:  23760485     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Scientific ocean drilling has revealed a deep biosphere of widespread microbial life in sub-seafloor sediment. Microbial metabolism in the marine subsurface probably has an important role in global biogeochemical cycles, but deep biosphere activities are not well understood. Here we describe and analyse the first sub-seafloor metatranscriptomes from anaerobic Peru Margin sediment up to 159 metres below the sea floor, represented by over 1 billion complementary DNA (cDNA) sequence reads. Anaerobic metabolism of amino acids, carbohydrates and lipids seem to be the dominant metabolic processes, and profiles of dissimilatory sulfite reductase (dsr) transcripts are consistent with pore-water sulphate concentration profiles. Moreover, transcripts involved in cell division increase as a function of microbial cell concentration, indicating that increases in sub-seafloor microbial abundance are a function of cell division across all three domains of life. These data support calculations and models of sub-seafloor microbial metabolism and represent the first holistic picture of deep biosphere activities.
Authors:
William D Orsi; Virginia P Edgcomb; Glenn D Christman; Jennifer F Biddle
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.     Date:  2013-06-12
Journal Detail:
Title:  Nature     Volume:  499     ISSN:  1476-4687     ISO Abbreviation:  Nature     Publication Date:  2013 Jul 
Date Detail:
Created Date:  2013-07-12     Completed Date:  2013-08-09     Revised Date:  2013-09-09    
Medline Journal Info:
Nlm Unique ID:  0410462     Medline TA:  Nature     Country:  England    
Other Details:
Languages:  eng     Pagination:  205-8     Citation Subset:  IM    
Affiliation:
Department of Geology and Geophysics, Woods Hole Oceanographic Institution, Woods Hole, Massachusetts 02543, USA. william.orsi@gmail.com
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MeSH Terms
Descriptor/Qualifier:
Anaerobiosis
Biomass
Cell Division / genetics
Colony Count, Microbial
DNA Repair / genetics
DNA, Complementary / analysis,  genetics
Gene Expression Profiling
Gene Expression Regulation, Bacterial
Gene Expression Regulation, Fungal
Geologic Sediments / microbiology*
Metabolic Networks and Pathways / genetics
Oceans and Seas
Seawater / microbiology
Sequence Analysis, DNA
Sulfates / metabolism
Transcriptome / genetics*
Water Microbiology
Chemical
Reg. No./Substance:
0/DNA, Complementary; 0/Sulfates
Comments/Corrections
Comment In:
Nat Rev Microbiol. 2013 Aug;11(8):508-9   [PMID:  23797174 ]

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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