| Gender-specific prediction of cardiac disease: importance of risk factors and exercise variables. | |
| | |
MedLine Citation:
|
PMID: 17053374 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
|
Current guidelines recommend targeting the intensity of preventive cardiovascular interventions to the level of the patient's risk, which is usually obtained from a global risk score such as the Framingham equations. However, a large proportion of asymptomatic U.S. women (approximately 80-90%) are classified as low risk by the Framingham score, although they have a 1 in 2 chance of dying from cardiovascular disease (CVD) during their lifetime. A promising avenue for improving CVD risk stratification has come from recent studies evaluating the prognostic value of exercise testing in asymptomatic populations using test variables that are not related to exercise-induced ST-segment depression. In particular, it has been shown that 2 easily obtained noninvasive measures, low exercise capacity and slow heart rate recovery, have been linked to increased CVD and all-cause death in both women and men. These 2 simple yet powerful measures of risk that are readily available are useful tools for the practicing cardiologist who desires more accurate assessment of risk in a female patient, particularly if she is deemed as intermediate risk by the Framingham score. In addition, both exercise capacity and heart rate recovery are at least partially modifiable by regular physical activity. Exercise recommendations of at least 30 minutes of moderate physical activity most days of the week have been associated with 30% to 50% reductions in coronary events and coronary mortality and should be recommended to all patients regardless of their Framingham risk score. |
| | |
Authors:
|
Sandra D'Amore; Samia Mora |
Related Documents
:
|
4026494 - Cardiac disability. the impact of coronary heart disease on patients' daily activities. 8296734 - Prediction of atherosclerotic cardiovascular death in men using a prognostic score. 7503104 - Lack of effect of exercise training on dehydroepiandrosterone-sulfate. 7794314 - Exercise tomographic thallium-201 imaging in patients with severe coronary artery disea... 9553794 - Evaluation of the role of carnobacterium piscicola in spoilage of vacuum- and modified-... 1235154 - Effect of a season of ice hockey on energy capacities and associated functions. |
Publication Detail:
|
Type: Journal Article; Review |
Journal Detail:
|
Title: Cardiology in review Volume: 14 ISSN: 1538-4683 ISO Abbreviation: Cardiol Rev Publication Date: 2006 Nov-Dec |
Date Detail:
|
Created Date: 2006-10-20 Completed Date: 2006-11-09 Revised Date: - |
Medline Journal Info:
|
Nlm Unique ID: 9304686 Medline TA: Cardiol Rev Country: United States |
Other Details:
|
Languages: eng Pagination: 281-5 Citation Subset: IM |
Affiliation:
|
Division of Preventive Medicine, Brigham and Women's Hospital/Harvard Medical School, Boston, Massachusetts 02215, USA. |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
Cardiovascular Diseases
/
etiology*,
mortality Exercise Test* Female Heart Rate Humans Physical Endurance Prognosis Risk Assessment / methods Risk Factors Women's Health* |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: Lipid abnormalities in women: data for risk, data for management.
Next Document: The metabolic syndrome in women.