Document Detail

Gender-related differences in target organ damage in untreated patients with essential hypertension.
MedLine Citation:
PMID:  16617189     Owner:  NLM     Status:  MEDLINE    
We examined the gender-related differences in target organ damage in 220 untreated patients with essential hypertension (106 men and 114 women). As the indices of target organ damage, we examined the left ventricular mass index and the intima-media thickness in the carotid and femoral arteries obtained from echocardiography. In a multiple regression model, there was a significant positive correlation between the intima-media thickness and age in both groups. In men, there was a significant positive correlation between the left ventricular mass index and age, as well as the diastolic blood pressure, and body mass index. In women, there was a significant positive correlation between the left ventricular mass index and age, as well as plasma renin activity and smoking. In conclusion, there are gender-related differences in the contributing factors, which relate to left ventricular hypertrophy in patients with essential hypertension.
Makoto Saitoh; Hideya Nishimura; Toshiro Tanaka; Teruo Kondoh
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Publication Detail:
Type:  Journal Article     Date:  2006-04-17
Journal Detail:
Title:  Internal medicine (Tokyo, Japan)     Volume:  45     ISSN:  1349-7235     ISO Abbreviation:  Intern. Med.     Publication Date:  2006  
Date Detail:
Created Date:  2006-04-17     Completed Date:  2006-07-24     Revised Date:  2006-08-04    
Medline Journal Info:
Nlm Unique ID:  9204241     Medline TA:  Intern Med     Country:  Japan    
Other Details:
Languages:  eng     Pagination:  377-83     Citation Subset:  IM    
Division of Cardiology, Department of Internal Medicine, Nishio Municipal Hospital, Nishio.
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MeSH Terms
Carotid Arteries / pathology
Femoral Artery / pathology
Hypertension / blood,  epidemiology*,  pathology*,  physiopathology
Hypertrophy, Left Ventricular / epidemiology
Middle Aged
Multivariate Analysis
Retrospective Studies
Risk Factors
Sex Factors
Tunica Intima / pathology
Tunica Media / pathology

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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