| Gender-related differences in cardiomyopathy. | |
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MedLine Citation:
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PMID: 2492448 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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As with other cardiovascular diseases, there are sufficient data to suggest significant gender-related differences in the prevalence and presentation of congestive heart failure and myocardial diseases. From animal studies, it is apparent that there are sex-related differences in intrinsic ventricular function and in the cardiovascular response to various stimuli, which are at least partly modulated through direct effects of sex hormones on the heart. Although similar data are not available in humans, it seems likely that similar gender-related differences in cardiac function exist and may in part account for the observed differences in myocardial diseases in men and women. Additionally, genetic factors may contribute to these differences, as X-linked disorders may present differently in males and females. An awareness of the impact of sex-related factors is clearly important in the evaluation of any patient presenting with heart failure or cardiomyopathy and may alter both diagnostic and therapeutic considerations, as well as broaden our basic knowledge and understanding of the pathogenetic mechanisms involved in myocardial dysfunction. |
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Authors:
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B A Berko |
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Publication Detail:
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Type: Comparative Study; Journal Article; Review |
Journal Detail:
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Title: Cardiovascular clinics Volume: 19 ISSN: 0069-0384 ISO Abbreviation: Cardiovasc Clin Publication Date: 1989 |
Date Detail:
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Created Date: 1989-03-23 Completed Date: 1989-03-23 Revised Date: 2006-11-15 |
Medline Journal Info:
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Nlm Unique ID: 0213744 Medline TA: Cardiovasc Clin Country: UNITED STATES |
Other Details:
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Languages: eng Pagination: 285-300 Citation Subset: IM |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Cardiomyopathies*
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epidemiology,
etiology Cardiomyopathy, Dilated / genetics Cardiovascular System / metabolism Diabetes Complications Fabry Disease / genetics Female Gonadal Steroid Hormones / physiology Humans Linkage (Genetics) Male Mucopolysaccharidoses / genetics Muscular Dystrophies / genetics Pedigree Sex Characteristics* X Chromosome / ultrastructure |
| Chemical | |
Reg. No./Substance:
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0/Gonadal Steroid Hormones |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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