Document Detail

Gender impact on first trimester markers in Down syndrome screening.
MedLine Citation:
PMID:  12478634     Owner:  NLM     Status:  MEDLINE    
The influence of fetal gender on the level in the first trimester of the serological markers alpha-fetoprotein (AFP), pregnancy-associated plasma protein-A (PAPP-A) and free beta human chorionic gonadotropin (betahCG) and on nuchal translucency is described for 2637 singleton pregnancies with normal outcome. Mean log MoM values for pregnancies with female and male fetuses were calculated using regression of log marker values on gestational age expressed as crown rump length and on maternal weight. A pronounced gender impact was found for free betahCG, being 16% higher for female than for male fetuses.
Severin Olesen Larsen; Karen R Wøjdemann; Anne-Cathrine Shalmi; Karin Sundberg; Michael Christiansen; Ann Tabor
Related Documents :
20521874 - Screening for fetal trisomy 21 in gestational weeks 6 and 7.
1283634 - Prospective intervention trial of a screening protocol to identify fetal trisomy 18 usi...
8649704 - The use of second-trimester genetic sonogram in guiding clinical management of patients...
18818504 - X pentasomy in an intracytoplasmic sperm injection pregnancy detected by nuchal translu...
24826864 - Screening and management of hypothyroidism in pregnancy: results of an asian survey.
15826674 - Fertility in south australian commercial merino flocks: sources of reproductive wastage.
Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Prenatal diagnosis     Volume:  22     ISSN:  0197-3851     ISO Abbreviation:  Prenat. Diagn.     Publication Date:  2002 Dec 
Date Detail:
Created Date:  2002-12-12     Completed Date:  2003-06-03     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  8106540     Medline TA:  Prenat Diagn     Country:  England    
Other Details:
Languages:  eng     Pagination:  1207-8     Citation Subset:  IM    
Copyright Information:
Copyright 2002 John Wiley & Sons, Ltd.
Department of Clinical Biochemistry, Statens Serum Institut, Copenhagen, Denmark.
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Biological Markers / blood*
Chorionic Gonadotropin, beta Subunit, Human / blood
Denmark / epidemiology
Down Syndrome / diagnosis*,  epidemiology
Mass Screening
Neck / embryology,  ultrasonography
Pregnancy / blood*
Pregnancy Trimester, First
Pregnancy-Associated Plasma Protein-A / analysis
Prenatal Diagnosis
Sex Characteristics*
alpha-Fetoproteins / analysis
Reg. No./Substance:
0/Biological Markers; 0/Chorionic Gonadotropin, beta Subunit, Human; 0/alpha-Fetoproteins; EC 3.4.24.-/Pregnancy-Associated Plasma Protein-A

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

Previous Document:  The association between fetal pyelectasis on second trimester ultrasound scan and aneuploidy among 2...
Next Document:  Prenatal diagnosis and treatment of fetal long QT syndrome: a case report.