Document Detail

Gender and fat metabolism during exercise: a review.
MedLine Citation:
PMID:  9822793     Owner:  NLM     Status:  MEDLINE    
We examined the evidence for greater fat utilization by women during exercise and the potential gender differences in specific cellular processes. Results from well-controlled studies show that, compared to men, women oxidize more fat during submaximal exercise, resulting in the relative sparing of muscle glycogen. Mature female rats use less muscle glycogen during running and can run longer than male counterparts. Circulating estrogen is critical to these observations, as shown by studies where male rats were treated with estrogen. Estrogen-treated male rats use less muscle glycogen during exercise and can run longer than untreated males. The cellular mechanisms and factors underlying these findings are unknown and certainly multifactorial. We offer some information that, unfortunately, does not lead to any natural conclusion. However, this area is certainly ripe for research.
C A Tate; R W Holtz
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't; Review    
Journal Detail:
Title:  Canadian journal of applied physiology = Revue canadienne de physiologie appliquée     Volume:  23     ISSN:  1066-7814     ISO Abbreviation:  Can J Appl Physiol     Publication Date:  1998 Dec 
Date Detail:
Created Date:  1999-01-21     Completed Date:  1999-01-21     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  9306274     Medline TA:  Can J Appl Physiol     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  570-82     Citation Subset:  IM; S    
Department of Pharmacological and Pharmaceutical Sciences, University of Houston, TX 77204, USA.
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MeSH Terms
Exercise / physiology*
Fatty Acids / metabolism
Glycogen / metabolism
Menstrual Cycle / physiology
Mitochondria / metabolism
Muscle, Skeletal / metabolism
Sex Characteristics*
Reg. No./Substance:
0/Fatty Acids; 9005-79-2/Glycogen

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