Document Detail

Gender effects in dietary histidine-induced anorexia.
MedLine Citation:
PMID:  15975494     Owner:  NLM     Status:  MEDLINE    
OBJECTIVE: Histamine, a derivative of histidine, decreases food intake by activation of histamine neurons. The aim of the present study was to clarify gender-related differences in food intake through the histidine-histamine neuron system. METHODS: Male, female, and ovariectomized rats were fed a histidine-enriched diet or a control diet with the cafeteria method. RESULTS: The suppressive effect of histidine on food intake was greater in female rats than in male rats, and the suppressive effect of histidine on food intake was less in ovariectomized rats than in female rats. CONCLUSION: Our results indicate that females are more sensitive than males to dietary histidine-induced anorexia.
Seiichi Kasaoka; Yumi Kawahara; Setsuko Inoue; Makiko Tsuji; Hideo Kato; Takahide Tsuchiya; Hiromichi Okuda; Shigeru Nakajima
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Nutrition (Burbank, Los Angeles County, Calif.)     Volume:  21     ISSN:  0899-9007     ISO Abbreviation:  Nutrition     Publication Date:    2005 Jul-Aug
Date Detail:
Created Date:  2005-06-24     Completed Date:  2005-11-21     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  8802712     Medline TA:  Nutrition     Country:  United States    
Other Details:
Languages:  eng     Pagination:  855-8     Citation Subset:  IM    
Department of Health and Nutrition, Bunkyo University Women's College, Kanagawa, Japan.,jp
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MeSH Terms
Anorexia / chemically induced*,  metabolism
Energy Intake / drug effects*
Histamine / metabolism
Histidine / administration & dosage*,  metabolism,  toxicity*
Models, Animal
Obesity / prevention & control
Rats, Wistar
Sex Factors
Reg. No./Substance:
51-45-6/Histamine; 71-00-1/Histidine

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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