Document Detail

Gender does matter in perinatal medicine.
MedLine Citation:
PMID:  15192298     Owner:  NLM     Status:  MEDLINE    
OBJECTIVE: To investigate complications and outcome of pregnancies with male and female fetuses. METHODS: A population-based study comparing all singleton deliveries between the years 1988 and 1999 was performed. We compared pregnancies with male vs. female fetuses. Patients with a previous cesarean section (CS) were excluded from the study. Statistical analyses with the Mantel-Haenszel technique and multiple logistic regression models were performed to control for confounders. RESULTS: During the study period there were 55,891 deliveries of male and 53,104 deliveries of female neonates. Patients carrying male fetuses had higher rates of gestational diabetes mellitus (OR = 1.1; 95% CI 1.01-1.12; p = 0.012), fetal macrosomia (OR = 2.0; 95% CI 1.8-2.1; p < 0.001), failure to progress during the first and second stages of labor (OR = 1.2; 95% CI 1.1-1.3; p < 0.001 and OR = 1.4; 95% CI 1.3-1.5; p < 0.001, respectively), cord prolapse (OR = 1.3; 95% CI 1.1-1.6; p = 0.014), nuchal cord (OR = 1.2; 95% CI 1.1-1.2; p < 0.001) and true umbilical cord knots (OR = 1.5; 95% CI 1.3-1.7; p < 0.001). Higher rates of CS were found among male compared with female neonates (8.7 vs. 7.9%; OR = 1.1; 95% CI 1.06-1.16; p < 0.001). Using three multivariate logistic regression models and controlling for birth weight and gestational age, male gender was significantly associated with non-reassuring fetal heart rate patterns (OR = 1.5; 95% CI 1.4-1.6; p < 0.001), low Apgar scores at 5 min (OR = 1.5; 95% CI 1.3-1.8; p < 0.001) and CS (OR = 1.2; 95%CI 1.2-1.3; p < 0.001). Controlling for possible confounders like gestational diabetes, cord prolapse, failed induction, nonprogressive labor, fetal macrosomia, nuchal cord and true umbilical cord knots using the Mantel-Haenszel technique did not change the significant association between male gender and CS. CONCLUSION: Male gender is an independent risk factor for adverse pregnancy outcome.
Eyal Sheiner; Amalia Levy; Miriam Katz; Reli Hershkovitz; Elad Leron; Moshe Mazor
Related Documents :
20003068 - Maternal diet during pregnancy and allergic sensitization in the offspring by 5 yrs of ...
22515548 - "double trouble" or an amplification of the triploidy phenotype?
16417548 - Community-based, prospective, controlled study of obstetric and neonatal outcome of 179...
23065298 - Racial disparities in economic and clinical outcomes of pregnancy among medicaid recipi...
16294308 - Proteome analysis of human amnion and amniotic fluid by two-dimensional electrophoresis...
10573038 - Seven years of intracytoplasmic sperm injection and follow-up of 1987 subsequent children.
Publication Detail:
Type:  Comparative Study; Journal Article    
Journal Detail:
Title:  Fetal diagnosis and therapy     Volume:  19     ISSN:  1015-3837     ISO Abbreviation:  Fetal. Diagn. Ther.     Publication Date:    2004 Jul-Aug
Date Detail:
Created Date:  2004-06-11     Completed Date:  2005-01-07     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  9107463     Medline TA:  Fetal Diagn Ther     Country:  Switzerland    
Other Details:
Languages:  eng     Pagination:  366-9     Citation Subset:  IM    
Copyright Information:
Copyright 2004 S. Karger AG, Basel
Department of Obstetrics and Gynecology, Faculty of Health Sciences, Soroka University Medical Center, Ben Gurion, Israel.
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Chi-Square Distribution
Confidence Intervals
Fetal Diseases / epidemiology
Infant, Newborn
Logistic Models
Odds Ratio
Perinatal Care* / statistics & numerical data
Sex Characteristics*

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

Previous Document:  Preterm deliveries among women with MacDonald cerclage performed due to cervical incompetence.
Next Document:  Antenatal necrotic injury in severe twin-to-twin transfusion syndrome. A case and review.