Document Detail

Gender differences in systolic tissue velocity: role of left ventricular length.
MedLine Citation:
PMID:  19720628     Owner:  NLM     Status:  MEDLINE    
AIMS: Previous research has described differences in left ventricular (LV) systolic tissue velocity between genders. This study aimed to determine the association between LV tissue velocity and LV size in healthy controls and in those with type 2 diabetes (T2DM). METHODS AND RESULTS: LV tissue velocities were measured in 71 controls and 222 patients with T2DM by pulsed-wave Doppler and colour-coded tissue Doppler (TDI) during systole (S' and S(m)) and diastole (early, E' and E(m), and late, A' and A(m)) at the basal septum and lateral wall. Both systolic tissue velocities were higher in males than in females within controls (S': 7.3 +/- 1.2 vs. 6.6 +/- 1.0 cm/s; P = 0.017, S(m): 6.2 +/- 1.0 vs. 5.5 +/- 0.7 cm/s; P = 0.002) but only by colour-coded TDI in patients with T2DM (S(m): 5.7 +/- 1.7 vs. 4.9 +/- 1.7 cm/s; P = 0.025). Correction for LV length negated the difference between genders in the controls and patients with T2DM (P > 0.05 for all). In controls, LV length was the strongest predictor of S' (beta = 0.393, P = 0.002), whereas height was the strongest predictor of S(m) (beta = 0.394, P = 0.003). CONCLUSION: In controls, systolic tissue velocities are significantly higher in males compared with females, which may be explained by the increased chamber size of men.
David J Holland; James E Sharman; Rodel L Leano; Thomas H Marwick
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't     Date:  2009-08-30
Journal Detail:
Title:  European journal of echocardiography : the journal of the Working Group on Echocardiography of the European Society of Cardiology     Volume:  10     ISSN:  1532-2114     ISO Abbreviation:  Eur J Echocardiogr     Publication Date:  2009 Dec 
Date Detail:
Created Date:  2009-11-05     Completed Date:  2010-01-26     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  100890618     Medline TA:  Eur J Echocardiogr     Country:  England    
Other Details:
Languages:  eng     Pagination:  941-6     Citation Subset:  IM    
Department of Medicine, Princess Alexandra Hospital, The University of Queensland, Brisbane, Queensland, Australia.
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MeSH Terms
Analysis of Variance
Case-Control Studies
Diabetes Mellitus, Type 2 / physiopathology*,  ultrasonography*
Echocardiography, Doppler / methods*
Image Interpretation, Computer-Assisted
Linear Models
Middle Aged
Sex Factors
Systole / physiology*
Ventricular Dysfunction, Left / physiopathology*,  ultrasonography*

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