Document Detail


Gender differences in systolic tissue velocity: role of left ventricular length.
MedLine Citation:
PMID:  19720628     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
AIMS: Previous research has described differences in left ventricular (LV) systolic tissue velocity between genders. This study aimed to determine the association between LV tissue velocity and LV size in healthy controls and in those with type 2 diabetes (T2DM). METHODS AND RESULTS: LV tissue velocities were measured in 71 controls and 222 patients with T2DM by pulsed-wave Doppler and colour-coded tissue Doppler (TDI) during systole (S' and S(m)) and diastole (early, E' and E(m), and late, A' and A(m)) at the basal septum and lateral wall. Both systolic tissue velocities were higher in males than in females within controls (S': 7.3 +/- 1.2 vs. 6.6 +/- 1.0 cm/s; P = 0.017, S(m): 6.2 +/- 1.0 vs. 5.5 +/- 0.7 cm/s; P = 0.002) but only by colour-coded TDI in patients with T2DM (S(m): 5.7 +/- 1.7 vs. 4.9 +/- 1.7 cm/s; P = 0.025). Correction for LV length negated the difference between genders in the controls and patients with T2DM (P > 0.05 for all). In controls, LV length was the strongest predictor of S' (beta = 0.393, P = 0.002), whereas height was the strongest predictor of S(m) (beta = 0.394, P = 0.003). CONCLUSION: In controls, systolic tissue velocities are significantly higher in males compared with females, which may be explained by the increased chamber size of men.
Authors:
David J Holland; James E Sharman; Rodel L Leano; Thomas H Marwick
Related Documents :
11205928 - Clinical characteristics influence left and right ventricular diastolic function in hea...
2188838 - Diastolic function and heart failure: an overview.
8800998 - Detection of abnormal aortic elastic properties in asymptomatic patients with marfan sy...
3985058 - Application of doppler echocardiography in the assessment of fetal cardiac disease.
1638108 - The autonomic nervous system and cardiac arrhythmias.
17655948 - Treatment of acute myocardial infarction in pregnancy with coronary artery balloon angi...
Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't     Date:  2009-08-30
Journal Detail:
Title:  European journal of echocardiography : the journal of the Working Group on Echocardiography of the European Society of Cardiology     Volume:  10     ISSN:  1532-2114     ISO Abbreviation:  Eur J Echocardiogr     Publication Date:  2009 Dec 
Date Detail:
Created Date:  2009-11-05     Completed Date:  2010-01-26     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  100890618     Medline TA:  Eur J Echocardiogr     Country:  England    
Other Details:
Languages:  eng     Pagination:  941-6     Citation Subset:  IM    
Affiliation:
Department of Medicine, Princess Alexandra Hospital, The University of Queensland, Brisbane, Queensland, Australia.
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Descriptor/Qualifier:
Analysis of Variance
Case-Control Studies
Diabetes Mellitus, Type 2 / physiopathology*,  ultrasonography*
Echocardiography, Doppler / methods*
Female
Humans
Image Interpretation, Computer-Assisted
Linear Models
Male
Middle Aged
Sex Factors
Systole / physiology*
Ventricular Dysfunction, Left / physiopathology*,  ultrasonography*

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


Previous Document:  Bacterial nitric oxide detoxification prevents host cell S-nitrosothiol formation: a novel mechanism...
Next Document:  Werner syndrome as a possible cause of non-alcoholic steatohepatitis.