Document Detail

Gender differences in metabolism; nutrition and supplements.
MedLine Citation:
PMID:  11101268     Owner:  NLM     Status:  MEDLINE    
For many decades researchers did not consider that there were any differences between the genders in the metabolic response to exercise. As a result, nutritional recommendations and exercise training prescriptions have not considered the potential for gender specific responses. More recently, we and others have demonstrated that females oxidize proportionately more lipid and less carbohydrate during endurance exercise as compared to males. The oxidation of amino acids is similarly lower in females as compared to males during exercise. These gender differences are partially mediated by a higher estrogen concentration in females. Specific areas where there are gender differences in nutritional/supplement recommendations include carbohydrate (CHO) nutrition, protein requirements and creatine (CRM) supplementation. We have shown that females do not carbohydrate load in response to an increase in dietary carbohydrate when expressed as a percentage of total energy intake (i.e., 55-75%), however if they consume >8 g CHOxkg(-1)xd(-1), they show similar increases as compared to males. Top sport male and female athletes require somewhat more dietary protein as compared to sedentary persons. The maximal increase is approximately 100% for elite male athletes and approximately 50-60% for elite female athletes. Fortunately, most athletes habitually consume this level of protein intake. We have recently demonstrated that females show a lesser increase in lean body mass following acute CRM loading as compared to males. Females also did not show reductions in protein breakdown in response to CRM loading, whereas males did. In the future I expect that there will be further research from which gender specific nutritional/supplement recommendations can be made.
M A Tarnopolsky
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Publication Detail:
Type:  Journal Article; Review    
Journal Detail:
Title:  Journal of science and medicine in sport / Sports Medicine Australia     Volume:  3     ISSN:  1440-2440     ISO Abbreviation:  J Sci Med Sport     Publication Date:  2000 Sep 
Date Detail:
Created Date:  2001-03-15     Completed Date:  2001-05-31     Revised Date:  2009-11-03    
Medline Journal Info:
Nlm Unique ID:  9812598     Medline TA:  J Sci Med Sport     Country:  AUSTRALIA    
Other Details:
Languages:  eng     Pagination:  287-98     Citation Subset:  IM    
McMaster University, Department of Medicine, (Neurology and Rehabilitation), McMaster University Medical Centre, Hamilton, Ontario, Canada.
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MeSH Terms
Carbohydrate Metabolism
Dietary Supplements
Energy Metabolism*
Exercise / physiology*
Lipid Metabolism
Muscles / metabolism
Nutritional Physiological Phenomena
Oxygen Consumption
Proteins / metabolism
Sex Characteristics*
Reg. No./Substance:

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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