Document Detail


Gender differences in AIDS-associated Kaposi sarcoma in Harare, Zimbabwe.
MedLine Citation:
PMID:  17146369     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Reasons for gender-related differences in the risk of AIDS-related Kaposi sarcoma (AIDS-KS) are unknown. Four hundred thirty-eight male and 166 female AIDS-KS patients were evaluated in Harare, Zimbabwe. Female patients were younger than male patients in this study (median of 33 vs. 38 years; P < 0.001), mirroring the epidemiology of AIDS in Zimbabwe. In a multivariate model adjusted for CD4 T-cell count, age, prior radiation treatment, and chemotherapy, women were more likely to report fever, diaphoresis, or weight loss (odds ratio = 1.7, 95% confidence interval: 1.1 to 2.7; P = 0.009). These findings suggest an increased severity of KS or other unidentified infections among women with AIDS-KS in Zimbabwe.
Authors:
Amie L Meditz; Margaret Borok; Samantha MaWhinney; Ivy Gudza; Buxton Ndemera; Lovemore Gwanzura; Thomas B Campbell
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Publication Detail:
Type:  Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Journal of acquired immune deficiency syndromes (1999)     Volume:  44     ISSN:  1525-4135     ISO Abbreviation:  J. Acquir. Immune Defic. Syndr.     Publication Date:  2007 Mar 
Date Detail:
Created Date:  2007-02-28     Completed Date:  2007-04-05     Revised Date:  2007-12-03    
Medline Journal Info:
Nlm Unique ID:  100892005     Medline TA:  J Acquir Immune Defic Syndr     Country:  United States    
Other Details:
Languages:  eng     Pagination:  306-8     Citation Subset:  IM; X    
Affiliation:
Division of Infectious Diseases, Department of Medicine, University of Colorado Health Sciences Center, 4200 East Ninth Avenue, Denver, CO 80262, USA.
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MeSH Terms
Descriptor/Qualifier:
AIDS-Related Opportunistic Infections / physiopathology*
Adolescent
Adult
Aged
Female
Fever
Gender Identity
HIV Infections / complications*
Humans
Male
Middle Aged
Multivariate Analysis
Sarcoma, Kaposi / physiopathology*
Sex Characteristics*
Sweating
Weight Loss
Zimbabwe
Grant Support
ID/Acronym/Agency:
AI 054907/AI/NIAID NIH HHS; CA 79389/CA/NCI NIH HHS; TW 0123/TW/FIC NIH HHS

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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