Document Detail

Gender difference in arrhythmic occurrences in patients with nonischemic dilated cardiomyopathy and implantable cardioverter-defibrillator.
MedLine Citation:
PMID:  20339977     Owner:  NLM     Status:  MEDLINE    
Previous studies indicated that women were less likely to experience ventricular arrhythmia recurrence than men among patients with coronary artery disease and implantable cardioverter defibrillator (ICD). However, it is not clear whether the risk for ventricular tachyarrhythmia is gender-dependent in patients with nonischemic dilated cardiomyopathy. This study included 173 consecutive nonischemic dilated cardiomyopathy patients with a left ventricular ejection fraction of <45% (122 men and 51 women), who received ICD therapy between 1990 and 2008. The average follow-up period was 33 +/- 28 months. There was no significant difference in event-free rates of appropriate ICD therapy between genders for all patients (P = 0.15) and by indication of ICD (primary prevention: P = 0.43, secondary prevention: P = 0.24). There was also no significant difference in event-free rates of electrical storm between genders (P = 0.17). In high-risk patients with nonischemic dilated cardiomyopathy who received ICD, there was no gender difference in the incidence of appropriate ICD therapy or electrical storm.
Atsushi Takahashi; Tsuyoshi Shiga; Morio Shoda; Kohei Tanizaki; Tetsuyuki Manaka; Koichiro Ejima; Hiroshi Kasanuki; Nobuhisa Hagiwara
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Publication Detail:
Type:  Comparative Study; Journal Article     Date:  2010-03-26
Journal Detail:
Title:  Heart and vessels     Volume:  25     ISSN:  1615-2573     ISO Abbreviation:  Heart Vessels     Publication Date:  2010 Mar 
Date Detail:
Created Date:  2010-03-26     Completed Date:  2010-06-10     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  8511258     Medline TA:  Heart Vessels     Country:  Japan    
Other Details:
Languages:  eng     Pagination:  150-4     Citation Subset:  IM    
Department of Cardiology, Tokyo Women's Medical University, 8-1 Kawada-cho, Shinjuku-ku, Tokyo, 162-8666, Japan.
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MeSH Terms
Cardiomyopathy, Dilated / complications,  mortality,  physiopathology,  therapy*
Chi-Square Distribution
Defibrillators, Implantable*
Disease-Free Survival
Electric Countershock / adverse effects,  instrumentation*
Kaplan-Meiers Estimate
Middle Aged
Proportional Hazards Models
Retrospective Studies
Risk Assessment
Risk Factors
Sex Factors
Stroke Volume
Tachycardia, Ventricular / etiology,  mortality,  physiopathology,  prevention & control*
Time Factors
Treatment Outcome
Ventricular Fibrillation / etiology,  mortality,  physiopathology,  prevention & control*
Ventricular Function, Left

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