| [Gemstone computed tomography in the evaluation of material distribution in pulmonary parenchyma for pulmonary embolism]. | |
| | |
MedLine Citation:
|
PMID: 22333104 Owner: NLM Status: In-Data-Review |
Abstract/OtherAbstract:
|
OBJECTIVE: To present our initial experiences with pulmonary high-definition multidetector computed tomography (HDCT) in patients with acute venous thromboembolism (AVTE) to evaluate their corresponding clinical manifestations. METHODS: Since December 2009 to March 2010, 23 AVTE patients underwent HDCT at our hospital. Pulmonary embolism (PE) was diagnosed based on the 3D-reconstructed images of computed tomography pulmonary angiography (CTPA). The postprocessed data were collected by spectral imaging system software to detect the iodine distribution maps. Perfusion defects, calculated as the values of iodine content, were compared with those of normal lung parenchymal perfusion in the absence of PE. RESULTS: Among them, 14 AVTE patients were definitely diagnosed with PE. Prior to anticoagulant therapy, their values of iodine content in defective perfusion area were significantly lower than those in normal perfusion area. After a 3-month anticoagulant therapy, the values of iodine content for the defective perfusion area increased significantly (P < 0.05). There was no significant correlation between the values of iodine content for segmental/subsegmental filling defect area and clinical risk score of DVT (r = 2.68, P > 0.05). But there was a significant negative correlation between the values of iodine content for segmental/subsegmental filling defection area and clinical probability score of PE (r = 0.78, P < 0.05). CONCLUSION: HDCT is a promising modality of visualizing pulmonary microvasculature as a correlative manifestation of regional perfusion. PE results in hypoperfusion with decreased values of iodine content in affected lung parenchyma. Hemodynamic changes in affected areas correlate with the severity of clinical manifestations of PE. |
| | |
Authors:
|
Lan Zhang; Lei Lü; Hua-Wei Wu; Hao Zhang; Ji-Wei Zhang |
Publication Detail:
|
Type: English Abstract; Journal Article |
Journal Detail:
|
Title: Zhonghua yi xue za zhi Volume: 91 ISSN: 0376-2491 ISO Abbreviation: Zhonghua Yi Xue Za Zhi Publication Date: 2011 Dec |
Date Detail:
|
Created Date: 2012-02-15 Completed Date: - Revised Date: - |
Medline Journal Info:
|
Nlm Unique ID: 7511141 Medline TA: Zhonghua Yi Xue Za Zhi Country: China |
Other Details:
|
Languages: chi Pagination: 3201-4 Citation Subset: IM |
Affiliation:
|
Department of Vascular Surgery, Department of Radiology, Renji Hospital, School of Medicine, Shanghai Jiaotong University, Shanghai 200127, China. |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
|
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: [Efficacies of carotid endarterectomy in the treatment of atherosclerotic carotid artery stenosis].
Next Document: [Clinical evaluation of restorative proctocolectomy with ileal pouch-anal anastomosis for ulcerative...