Document Detail


Gemcitabine induced myositis in patients with pancreatic cancer: case reports and topic review.
MedLine Citation:
PMID:  21811892     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Gemcitabine potential myotoxicity has been described in several cases of radiation recall and in patients treated with gemcitabine alone or in combination with other chemotherapy agents. We report two cases of gemcitabine related myositis identified at our institution, and perform a literature review of cases which meet the criteria for gemcitabine induced myositis associated to either radiation therapy or chemotherapy alone.
Authors:
Elena Pentsova; Anli Liu; Marc Rosenblum; Eileen O'Reilly; Xi Chen; Adília Hormigo
Publication Detail:
Type:  Case Reports; Journal Article     Date:  2011-08-03
Journal Detail:
Title:  Journal of neuro-oncology     Volume:  106     ISSN:  1573-7373     ISO Abbreviation:  J. Neurooncol.     Publication Date:  2012 Jan 
Date Detail:
Created Date:  2011-11-22     Completed Date:  2012-03-25     Revised Date:  2013-06-03    
Medline Journal Info:
Nlm Unique ID:  8309335     Medline TA:  J Neurooncol     Country:  United States    
Other Details:
Languages:  eng     Pagination:  15-21     Citation Subset:  IM    
Affiliation:
Department of Neurology, Memorial Sloan-Kettering Cancer Center, 1275 York Avenue, New York, NY 10065, USA.
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MeSH Terms
Descriptor/Qualifier:
Adenocarcinoma / complications*,  drug therapy*,  pathology
Anti-Inflammatory Agents / therapeutic use
Antimetabolites, Antineoplastic / adverse effects*,  therapeutic use
Deoxycytidine / adverse effects,  analogs & derivatives*,  therapeutic use
Dexamethasone / therapeutic use
Female
Humans
Magnetic Resonance Imaging
Male
Middle Aged
Muscle, Skeletal / pathology
Myositis / chemically induced*,  pathology
Pancreatic Neoplasms / complications*,  drug therapy*,  pathology
Radiotherapy / adverse effects
Thigh / pathology
Chemical
Reg. No./Substance:
0/Anti-Inflammatory Agents; 0/Antimetabolites, Antineoplastic; 50-02-2/Dexamethasone; 951-77-9/Deoxycytidine; B76N6SBZ8R/gemcitabine

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