| Gelastic epilepsy and dysprosodia in a case of late-onset right frontal seizures. | |
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MedLine Citation:
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PMID: 19733125 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Gelastic epilepsy (GE) is an uncommon type of seizure disorder characterized by stereotyped, unprovoked, inappropriate ictal laughter. GE is most frequently associated with hypothalamic hamartoma, with onset almost invariably occurring during childhood. GE also occurs occasionally with temporal and frontal cortical seizure foci. We describe an unusual case of senescent-onset GE with a right frontal seizure focus. In addition to laughter, dysprosodia was a clinical feature. Clinical and electroencephalographic evidence of seizure activity ceased on levetiracetam, and the patient showed concurrent improvement in cognitive function. We review the evidence for the cerebral representation of laughter and prosody, and discuss issues bearing on the differential diagnosis and management of GE. |
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Authors:
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Steven P Cercy; Joshua E Kuluva |
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Publication Detail:
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Type: Case Reports; Journal Article Date: 2009-09-03 |
Journal Detail:
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Title: Epilepsy & behavior : E&B Volume: 16 ISSN: 1525-5069 ISO Abbreviation: Epilepsy Behav Publication Date: 2009 Oct |
Date Detail:
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Created Date: 2009-10-06 Completed Date: 2009-12-07 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 100892858 Medline TA: Epilepsy Behav Country: United States |
Other Details:
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Languages: eng Pagination: 360-5 Citation Subset: IM |
Affiliation:
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Mental Health Service, Veterans Affairs New York Harbor Healthcare System, New York, NY, USA. steven.cercy@va.gov |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Aged, 80 and over Anticonvulsants / therapeutic use Electroencephalography Epilepsies, Partial / complications*, drug therapy Frontal Lobe / physiopathology* Humans Laughter* Magnetic Resonance Imaging / methods Male Neuropsychological Tests Seizures / complications*, pathology* Treatment Outcome |
| Chemical | |
Reg. No./Substance:
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0/Anticonvulsants |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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