| Gd-EOB-DTPA-enhanced magnetic resonance imaging findings of nondiffuse fatty change of the liver. | |
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MedLine Citation:
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PMID: 21084902 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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PURPOSE: To evaluate the difference in enhancement effects between the area of fatty change and the area of nonfatty change in patients with nondiffuse fatty change of the liver at gadolinium-ethoxybenzyl-diethylenetriamine pentaacetic acid (Gd-EOB-DTPA)-enhanced magnetic resonance (MR) imaging. METHODS: Thirteen patients with nondiffuse fatty change of the liver underwent Gd-EOB-DTPA-enhanced MR imaging including dynamic study using a 1.5-T MR unit. Dynamic contrast-enhanced (DCE) MR images were obtained at pre, arterial phase (25 seconds), portal phase (70 seconds), equilibrium phase (3 minutes), and hepatobiliary phase (10, 15, 20 minutes). The percentage differences of signal enhancement ratio were calculated from signal intensity measurement of the liver in each phase of DCE study and were compared between the area of fatty change and the area of nonfatty change in all phases. RESULTS: In the all phases on DCE study, there were no significant differences in the signal enhancement ratio between the area of fatty change (27.7% ± 14.8%, 58.2% ± 14.7%, 62.7% ± 10.6%, 80.4% ± 15.2%, 84.9% ± 16.2%, 88.0% ± 14.3%) and the area of nonfatty change (29.9% ± 16.6%, 54.9% ± 13.3%, 63.0% ± 8.8%, 75.7% ± 12.6%, 80.3% ± 15.7%, 86.4% ± 14.5%) (P = 0.613). CONCLUSIONS: Although our results are limited by the small number of patients, our results showed that the presence of fatty change of the liver did not affect the hepatic contrast enhancement effects of Gd-EOB-DTPA in all phases on dynamic study. This indicates that Gd-EOB-DTPA may be a reliable marker to identify areas of nondiffuse fatty change of the liver. |
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Authors:
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Akira Yamamoto; Tsutomu Tamada; Teruki Sone; Hiroki Higashi; Takenori Yamashita; Katsuyoshi Ito |
Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: Journal of computer assisted tomography Volume: 34 ISSN: 1532-3145 ISO Abbreviation: J Comput Assist Tomogr Publication Date: 2010 Nov-Dec |
Date Detail:
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Created Date: 2010-11-18 Completed Date: 2011-01-10 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 7703942 Medline TA: J Comput Assist Tomogr Country: United States |
Other Details:
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Languages: eng Pagination: 868-73 Citation Subset: IM |
Affiliation:
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Department of Radiology, Kawasaki Medical School, Kurashiki, Okayama, Japan. jiro@med.kawasaki-m.ac.jp |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Adult Contrast Media / administration & dosage* Fatty Liver / pathology* Female Gadolinium DTPA / administration & dosage* Humans Magnetic Resonance Imaging / methods* Male Middle Aged |
| Chemical | |
Reg. No./Substance:
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0/Contrast Media; 0/gadolinium ethoxybenzyl DTPA; 80529-93-7/Gadolinium DTPA |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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