| Gauze pledgetting versus endoscopic-guided aerosolized spray for nasal anesthesia before transnasal EGD: a prospective, randomized study. | |
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MedLine Citation:
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PMID: 19748613 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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BACKGROUND: Methods and efficacy of nasal anesthesia before ultrathin transnasal EGD (UT-EGD) are crucial for patient tolerance. OBJECTIVE: To compare patient tolerance, safety, and adverse events between cotton-tipped applicator primed gauze pledgetting (CTGP) and endoscopic-guided aerosolized spray (EGAS) methods of nasal anesthesia. DESIGN: We performed a prospective, randomized-controlled trial to compare procedural discomforts, optical quality, total procedure time, and adverse events between the CTGP and EGAS methods. SETTING: A large, tertiary referral hospital in Taiwan. PATIENTS: A total of 240 consecutive patients with epigastric discomfort were included in the study. INTERVENTION: The author performed all standardized nasal anesthesia and UT-EGD using a 5.9-mm diameter transnasal endoscope. MAIN OUTCOME MEASUREMENTS: Technical success, patient tolerability profiles, optical quality, total procedure time, and adverse events. RESULTS: There was no statistical difference in insertion failure rates between the 2 methods (CTGP 0% vs EGAS 5%, P = .07). When compared with the EGAS method, CTGP reduced pain during insertions through the inferior nasal meatus (3.4 +/- 0.5 vs 3.2 +/- 0.4, P = .006), middle nasal meatus (4.0 +/- 0.7 vs 3.4 +/- 0.5, P = .002), and upper esophageal sphincter (2.9 +/- 0.7 vs 2.6 +/- 0.8, P = .005). CTGP elicited less unpleasant taste, fewer gagging episodes, and less throat pain after examination. Both methods had similar safe hemodynamic profiles, low epistaxis rates (0% vs 2%, P = .46), and comparable visual capacity and procedure time. Although similar proportions of patients in both groups would like to receive the same procedure the next time, CTGP had a higher overall tolerance. CONCLUSION: Compared with the EGAS method, CTGP achieved a better tolerability profile and elicited less bad taste, fewer gagging episodes, and less throat pain after UT-EGD in Taiwanese patients. |
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Authors:
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Chi-Tan Hu |
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Publication Detail:
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Type: Comparative Study; Journal Article; Randomized Controlled Trial; Research Support, Non-U.S. Gov't Date: 2009-09-12 |
Journal Detail:
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Title: Gastrointestinal endoscopy Volume: 71 ISSN: 1097-6779 ISO Abbreviation: Gastrointest. Endosc. Publication Date: 2010 Jan |
Date Detail:
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Created Date: 2010-01-28 Completed Date: 2010-04-27 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 0010505 Medline TA: Gastrointest Endosc Country: United States |
Other Details:
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Languages: eng Pagination: 11-20 Citation Subset: IM |
Copyright Information:
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2010 American Society for Gastrointestinal Endoscopy. Published by Mosby, Inc. All rights reserved. |
Affiliation:
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Division of Gastroenterology and Research Centre for Hepatology, Department of Internal Medicine, Buddhist Tzu Chi General Hospital and Graduate Institute of Clinical Medicine, School of Medicine, Tzu Chi University, Hualien, Taiwan. chitan.hu@msa.hinet.net |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Administration, Inhalation Administration, Intranasal Administration, Topical Adult Anesthetics, Local* Duodenoscopy* Esophagoscopy* Female Gastroscopy* Humans Male Middle Aged Nose Prospective Studies Surgical Sponges |
| Chemical | |
Reg. No./Substance:
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0/Anesthetics, Local |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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