| Gating-ML: XML-based gating descriptions in flow cytometry. | |
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MedLine Citation:
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PMID: 18773465 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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The lack of software interoperability with respect to gating due to lack of a standardized mechanism for data exchange has traditionally been a bottleneck, preventing reproducibility of flow cytometry (FCM) data analysis and the usage of multiple analytical tools. To facilitate interoperability among FCM data analysis tools, members of the International Society for the Advancement of Cytometry (ISAC) Data Standards Task Force (DSTF) have developed an XML-based mechanism to formally describe gates (Gating-ML). Gating-ML, an open specification for encoding gating, data transformations and compensation, has been adopted by the ISAC DSTF as a Candidate Recommendation. Gating-ML can facilitate exchange of gating descriptions the same way that FCS facilitated for exchange of raw FCM data. Its adoption will open new collaborative opportunities as well as possibilities for advanced analyses and methods development. The ISAC DSTF is satisfied that the standard addresses the requirements for a gating exchange standard. |
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Authors:
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Josef Spidlen; Robert C Leif; Wayne Moore; Mario Roederer; ; Ryan R Brinkman |
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Publication Detail:
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Type: Journal Article; Research Support, N.I.H., Extramural |
Journal Detail:
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Title: Cytometry. Part A : the journal of the International Society for Analytical Cytology Volume: 73A ISSN: 1552-4930 ISO Abbreviation: Cytometry A Publication Date: 2008 Dec |
Date Detail:
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Created Date: 2008-11-21 Completed Date: 2009-08-11 Revised Date: 2010-09-21 |
Medline Journal Info:
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Nlm Unique ID: 101235694 Medline TA: Cytometry A Country: United States |
Other Details:
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Languages: eng Pagination: 1151-7 Citation Subset: IM |
Affiliation:
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Terry Fox Laboratory, BC Cancer Agency, Vancouver, British Columbia, Canada. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Cell Separation
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standards* Flow Cytometry / standards* Information Storage and Retrieval / standards* Information Systems / standards* Software / standards* |
| Grant Support | |
ID/Acronym/Agency:
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EB005034/EB/NIBIB NIH HHS; R01 EB005034-01/EB/NIBIB NIH HHS; R01 EB005034-02/EB/NIBIB NIH HHS; R01 EB005034-03/EB/NIBIB NIH HHS; R01 EB005034-04/EB/NIBIB NIH HHS |
| Comments/Corrections | |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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