Document Detail


Gatifloxacin-associated hypoglycemia.
MedLine Citation:
PMID:  18183859     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Fluoroquinolone antibiotics are widely employed in treating infectious diseases. Lately, reports of either hyperglycemia or hypoglycemia have appeared in the medical literature. Many patients are elderly and have underlying diabetes and renal insufficiency. Of these antibiotics, dysglycemia occurs more frequently with gatifloxacin (Tequin). While hypoglycemia usually occurs within the first three days of treatment, hyperglycemia often occurs later in the treatment course. The hypoglycemia may be profound and difficult to manage. We report 4 patients with hypoglycemia while taking gatifloxacin and review the relevant literature.
Authors:
Tauseef Ali; Ronald A Greenfield; Hal Scofield; Michael S Bronze
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Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  The Journal of the Oklahoma State Medical Association     Volume:  100     ISSN:  0030-1876     ISO Abbreviation:  J Okla State Med Assoc     Publication Date:  2007 Nov 
Date Detail:
Created Date:  2008-01-10     Completed Date:  2008-01-31     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  7503043     Medline TA:  J Okla State Med Assoc     Country:  United States    
Other Details:
Languages:  eng     Pagination:  425-8     Citation Subset:  IM    
Affiliation:
Department of Medicine, University of Oklahoma, Williams Pavilion, 1140 920 Stanton Young Blvd., OKC, OK 73104, USA.
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MeSH Terms
Descriptor/Qualifier:
Adult
Aged
Aged, 80 and over
Anti-Bacterial Agents / adverse effects*,  therapeutic use
Bacterial Infections / drug therapy
Diabetes Mellitus, Type 2 / complications
Fluoroquinolones / adverse effects*,  therapeutic use
Humans
Hypoglycemia / chemically induced*,  complications
Male
Chemical
Reg. No./Substance:
0/Anti-Bacterial Agents; 0/Fluoroquinolones; 112811-59-3/gatifloxacin

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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