| Gated-SPECT equilibrium radionuclide angiography in right ventricular assessment of patients with repaired tetralogy of Fallot. | |
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MedLine Citation:
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PMID: 17264773 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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BACKGROUND: The long-term prognosis of patients with tetralogy of Fallot (TF) who have undergone repair is determined by right ventricular dilatation resulting from residual pulmonary insufficiency. We have studied the values of right and left ventricle systolic function obtained by gated single photon emission computed tomography (SPECT) equilibrium radionuclide angiography (ERNA) in these patients. METHODS: A study population of 62 patients with surgically repaired TF underwent gated-SPECT ERNA to determine ejection fraction of the right and left ventricle and dimensions of the right ventricle and pulmonary infundibulum. Results were compared with those of a group of 11 patients without heart disease. RESULTS: RVEF (34% vs. 40%, P=0.02) and LVEF (49% vs. 54%, P=0.03) were significantly lower in patients with TF than in the control group. The RVEF and LVEF variation coefficients were 9% and 6.2%, respectively. Volumes of the right ventricle (P=0.003) were significantly greater than those of the control group, although variation coefficients were 15%. CONCLUSIONS: Gated-SPECT ERNA is a non-invasive method of assessing ejection fraction in patients with repaired TF. In these patients, the ejection fraction is decreased in both ventricles, whereas size of the right ventricle is significantly increased. Reproducibility of the RVEF calculation is good, but in the case of volumes it is suboptimal. |
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Authors:
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Ana P Caresia-Aróztegui; Santiago Aguadé-Bruix; Joan Castell-Conesa; Paloma Pifarré-Montaner; Gemma Cuberas-Borrós; Jaume Casaldàliga; Josep Girona; Guillermo Romero-Farina; Jaume Candell-Riera |
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Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: Nuclear medicine communications Volume: 28 ISSN: 0143-3636 ISO Abbreviation: Nucl Med Commun Publication Date: 2007 Mar |
Date Detail:
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Created Date: 2007-01-31 Completed Date: 2007-04-02 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 8201017 Medline TA: Nucl Med Commun Country: England |
Other Details:
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Languages: eng Pagination: 159-64 Citation Subset: IM |
Affiliation:
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Servicio de Medicina Nuclear, Hospital Universitari Vall d'Hebron, Barcelona, Spain. |
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| MeSH Terms | |
Descriptor/Qualifier:
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Adult Computer Simulation Erythrocytes / radionuclide imaging Female Follow-Up Studies Gated Blood-Pool Imaging / methods* Heart Ventricles / pathology Humans Male Models, Anatomic Prospective Studies Reproducibility of Results Stroke Volume / physiology Technetium / diagnostic use Tetralogy of Fallot / radionuclide imaging*, surgery* Tomography, Emission-Computed, Single-Photon / methods* Ventricular Function, Right / physiology |
| Chemical | |
Reg. No./Substance:
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7440-26-8/Technetium |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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